Academicians | Yangtze River Scholars | Outstanding Young Talent | Professors | Associate Professors


Juan Tan

 Department: Microbiology
 Address: Room 419, Department of Microbiology, College of life sciences, Nankai University
 Phone: 86-22-23500950
::Professional Education::

1999-2003    B.S. in Biological Technology, Yangzhou University, Yangzhou, China

2003-2008    Ph.D. in Microbiology, Nankai University, Tianjin, China

2008-2010    Postdoctoral Fellow, Department of Chemical Biology, College of Chemistry, Nankai University, Tianjin, China  

2010-           Associate Professor, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China

::Research Area::

1.    Molecular biology of retrovirus and related virus

2.    Interaction between virus and host cells

3.    Antiviral mechanism of host innate immunity

4.    Construction of bovine foamy virus vectors


::Honors and Awards::
::Representative Publications::

1.   Hu, X., W. Yang, R. Liu, Y. Geng, W. Qiao, and J. Tan*. 2014. N-Myc interactor inhibits prototype foamy virus by sequestering viral Tas protein in the cytoplasm. J Virol 88:7036-44.

2.   Liu, R., Y. Lin, R. Jia, Y. Geng, C. Liang, J. Tan*, and W. Qiao*. 2014. HIV-1 Vpr stimulates NF-kappaB and AP-1 signaling by activating TAK1. Retrovirology 11:45.

3.   Ma, Q. #, J. Tan#, X. Cui, D. Luo, M. Yu, C. Liang, and W. Qiao. 2014. Residues R(199)H(200) of prototype foamy virus transactivator Bel1 contribute to its binding with LTR and IP promoters but not its nuclear localization. Virology 449:215-23.

4.   Guo, H. Y., Y. G. Ma, Y. M. Gai, Z. B. Liang, J. Ma, Y. Su, Q. C. Zhang, Q. M. Chen, and J. Tan*. 2013. Bovine HEXIM1 inhibits bovine immunodeficiency virus replication through regulating BTat-mediated transactivation. Vet Res 44:21.

5.   Liu, R. #, J. Tan#, Y. Lin, R. Jia, W. Yang, C. Liang, Y. Geng, and W. Qiao. 2013. HIV-1 Vpr activates both canonical and noncanonical NF-kappaB pathway by enhancing the phosphorylation of IKKalpha/beta. Virology 439:47-56.

6.   Chang, R. #, J. Tan#, F. Xu, H. Han, Y. Geng, Y. Li, and W. Qiao. 2011. Lysine acetylation sites in bovine foamy virus transactivator BTas are important for its DNA binding activity. Virology 418:21-6.

7.   Wang, J. #, J. Tan#, H. Guo, Q. Zhang, R. Jia, X. Xu, Y. Geng, and W. Qiao. 2010. Bovine foamy virus transactivator BTas interacts with cellular RelB to enhance viral transcription. J Virol 84:11888-97.

8.   Tan, J., P. Hao, R. Jia, W. Yang, R. Liu, J. Wang, Z. Xi, Y. Geng, and W. Qiao. 2010. Identification and functional characterization of BTas transactivator as a DNA-binding protein. Virology 405:408-13.

9.   Tan, J., W. Qiao, J. Wang, F. Xu, Y. Li, J. Zhou, Q. Chen, and Y. Geng. 2008. IFP35 is involved in the antiviral function of interferon by association with the viral tas transactivator of bovine foamy virus. J Virol 82:4275-83.

10. Tan, J., W. Qiao, F. Xu, H. Han, Q. Chen, and Y. Geng. 2008. Dimerization of BTas is required for the transactivational activity of bovine foamy virus. Virology 376:236-41.


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