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蔡峻

 性    别:男
 职    称:教授
 所属部门:微生物学系
 招生专业:微生物学
 研究方向:
::教师简介::
博士、教授、博士生导师。

2000年毕业于浙江大学害虫综合治理专业,获博士学位。2000.9~2002.6,在南开大学生物学博士后流动站工作。2007.1~2008.1在丹麦哥本哈根大学分子生物学系访问学习。

目前研究方向:
1)苏云金芽胞杆菌、蜡状芽胞杆菌、枯草芽胞杆菌等生防微生物的杀虫、抗病的分子机理及其相关基因的表达调控
2)昆虫病理学研究,包括寄生蜂调控寄主血细胞免疫机理;苏云金杆菌毒素作用靶标昆虫细胞的结合位点及其导致寄主细胞死亡的机理。

教学:
目前承担本科生课程:基础生命科学,发育生物学;承担研究生课程:分子微生物学。
参与翻译专著2部。

现为国家精品视频公开课《生命科学漫谈》主持人,国家精品课《微生物发酵工程》课程组成员,教育部“科学素质教育系列公共课国家级教学团队”成员,校级精品课《基础生命科学》课程组主讲教师。

获“第十届天津市高校青年教师教学基本功竞赛”二等奖,“南开大学青年教师教学基本功竞赛”一等奖。指导本科生获南开大学本科生创新科研项目一等奖。2011年12月荣获南开大学第四届“良师益友”评选活动优秀导师,2016年获“宝钢优秀教师奖”。

科研:
主持国家自然科学基金、教育部出国留学人员科研启动基金、天津市自然科学基金等5项,参与国家、教育部、科技部、天津市科技攻关等项目5项。发表科研论文30余篇,其中SCI收录9篇。2010年获国家科技进步二等奖(排名第2),2003年获教育部提名国家自然科学奖二等奖(排名第4),获得发明专利3项。

通讯地址:天津市南开大学生命科学学院 ( 邮政编码 300071) 
电话: 022-2350 5964
电子邮件: caijun@nankai.edu.cn 

代表论文:
1.	Kun Jiang, Si-qi Mei, Ting-ting Wang, Jin-hua Pan, Yue-hua Chen, Jun Cai*.Vip3Aa induces apoptosis in cultured Spodoptera frugiperda (Sf9) cells. Toxicon, 2016,120 :49-56
2.	Yinyue Deng, Jien Wu, Wenfang Yin, Peng Li, Jianuan Zhou, Shaohua Chen, Fei He,Jun Cai, and Lian-Hui Zhang. Diffusible signal factor family signals provide a fitness advantage to Xanthomonas campestris pv. campestris in interspecies competition. Environmental Microbiology, 2016, 18(5):1534–1545
3.	Kun Jiang, Li-na Li, Jin-hua Pan, Ting-ting Wang, Yue-hua Chen, Jun Cai*. YvoA and CcpA Repress the Expression of chiB in Bacillus thuringiensis. Applied and Environmental Microbiology,2015,81(19):6548-6555
4.	Xie Chi?Chu, Jin Shi, Hai?Yun Jia, Peng?Fei Li,Yang Luo, Jun Cai , Yue?Hua Chen. Characterization of regulatory regions involved in the inducible expression of chiB in Bacillus thuringiensis. Archives of Microbiology. 2015, 197 (1): 53-63
5.	Yingde Shen, Ruibin Liu, Yuehua Chen, Jun Cai*. Identification of an Antifungal Bacillus Strain and Studies on Its Antifungal Active Ingredients. Proceedings of the 2012 International Conference on Applied Biotechnology (ICAB 2012), Lecture Notes in Electrical Engineering. Volume 251, 2014, pp 1637-1644
6.	Xiao Liang, Chuan Liu, Xie Chi-chu, Jun Cai* , Yue-hua Chen*. The direct repeat sequence upstream of Bacillus chitinase genes is cis-acting elements that negatively regulate heterologous expression in E. coli. Enzyme and Microbial Technology, 2012,50:280-286.
7.	Xie Chi-Chu, Yang Luo, Yue-Hua Chen*, Jun Cai. Construction of a Promoter-probe Vector for Bacillus thuringiensis: the Identification of cis-acting Elements of the chiA Locus. Current Microbiology, 2012,64(5):492-500.	
8.	Xueyong Zhou, Wei Qi, Jianbo Zhang, Tingting Zou , Guo Chen , Jun Cai*, and Xiang Huang .Spectroscopic nvestigation of the structure of protoxin protein isolated from Bacillus thuringiensis contacted with minerals. Biocontrol Science and Technology, 2010,20(8)841 – 852
9.	Dong Liu, Jun Cai, Chi-chu Xie, Chuan Liu and Yue-hua Chen. Purification and partial characterization of a 36-kDa chitinase from Bacillus thuringiensis subsp. colmeri, and its biocontrol potential. Enzyme and Microbial Technology. 2010,46:252–25646
10.	Liang Xiao, Chi-chu Xie, Jun Cai, Zhi-Jie Lin and Yue-Hua Chen. Identification and Characterization of a Chitinase-Produced Bacillus Showing Significant Antifungal Activity. Current Microbiology. 2009 ,58(5):528-33  
11.	Zhang, J. Cai, J. Deng, Y. Chen, Y. Ren, G.  Characterization of Melanin produced by a wild-type strain of Bacillus cereus. Frontiers of Biology in China, 2007. 2: 26~29
12.	Jun Cai*, Liang Xiao, Bing Yan, Yinyue Deng, Yuehua Chen, Gaixin Ren.Vip3A is responsible for the potency of Bt9816C culture supernatant against Helicoverpa armigera and Spodoptera exigua. Journal of General and Applied Microbiology. 2006,52(2)83-89  
13.	Zhong Zhang, Gong-yin Ye, Jun Cai, Cui Hu. Comparative venom toxicity between Pteromalus puparum and Nasonia vitripennis (Hymenoptera: Pteromalidae) toward the hemocytes of their natural hosts, non-target insects and cultured insect cells. Toxicon. 2005, 46(3):337-49 
14.	Jun Cai*, Rui-Bin Liu, Gai-Xin Ren. The toxicity of Bacillus thuringiensis 9816C to Spodoptera exigua related to the binding sites on BBMV. Insect Science. 2005, 12:429-433
15.	Jun Cai, Gong-yin Ye, Cui Hu.  Parasitization of Pieris rapae (Lepidopetera) by the pupal endoparisitoid Pteromalus puparum (Hymenoptera: Pteromalidae), suppresses haemocyte encapsulation. Journal of Insect Physiology. 2004,50:315-322 
16.	Yuehua Chen, Yinyue Deng, Jinhong Wang, Jun Cai, Gaixin Ren. Characterization of melanin produced by a wild-type strain of Bacillus thuringiensis.  Journal of General and Applied Microbiology. 2004, 50: 183-188. 



::主要学术论文::
::主要科研项目::