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靳永新

 性    别:女
 职    称:副教授
 所属部门:微生物学系
 招生专业:微生物学
 研究方向:微生物基因功能,病原菌致病机理
::教师简介::
个人简历
2002        南开大学 学士
2006        南开大学 博士
2009--2011  美国佛罗里达大学 联合培养博士
2011--2016  南开大学生命科学学院  讲师
2016--      南开大学生命科学学院  副教授

2002        B.S. Nankai University
2006        Ph.D. Nankai University
2009--2011  Joint Ph.D. University of Florida, USA
2011--2016  Nankai University College of Life Sciences, instructor
2016--      Nankai University College of Life Sciences, associate professor

研究方向
■ 致病菌毒性基因的表达调控及作用机制;
■ 致病菌耐药机理研究;

Research Fields
■ Regulation and function of pathogenic bacterial virulence factors 
■ Mechanisms of antibiotics resistance in pathogenic bacteria 

Selected Publications
1.	Pseudomonas aeruginosa enolase influences bacterial tolerance to oxidative stresses and virulence, Yuding Weng, Fei Chen, Yiwei Liu, Qiang Zhao, Xiaolei Pan, Chang Liu, Ronghao Chen, Zhihui Cheng, Shouguang Jin, Yongxin Jin, Weihui Wu. Frontiers in Microbiology. 
2.	HigB of Pseudomonas aeruginosa Enhances Killing of Phagocytes by Up-Regulating the Type III Secretion System in Ciprofloxacin Induced Persister Cell, Li M, Long Y, Liu Y, Liu Y, Chen C, Shi J, Zhang L, Jin Y, Yang L, Bai F, Jin S, Cheng Z and Wu W. Frontiers. in Cellular and Infection Microbiology, 6:125. 
3.	DeaD contributes to Pseudomonas aeruginosa virulence in a mouse acute pneumonia model. Tan H, Zhang L, Zhao Q, Chen R, Liu C, Weng Y, Peng Q, Bai F, Cheng Z, Jin S, Wu W, Jin Y. FEMS Microbiol Lett, 363(20). 
4.	Oligoribonuclease is required for the type III secretion system and pathogenesis of Pseudomonas aeruginosa. Chen G, Zhao Q, Zhu F, Chen R, Jin Y, Liu C, Pan X, Jin S, Wu W, Cheng Z. Microbiological Research, 188-189:90-6.
5.	Tan H, Zhang L, Weng Y, Chen R, Zhu F, Jin Y, Cheng Z, Jin S, Wu W. PA3297 Counteracts Antimicrobial Effects of Azithromycin in Pseudomonas aeruginosa. (2016) Front Microbiol.7:317.
6.	Chen R, Weng Y, Zhu F, Jin Y, Liu C, Pan X, Xia B, Cheng Z, Jin S, Wu W. Polynucleotide Phosphorylase Regulates Multiple Virulence Factors and the Stabilities of Small RNAs RsmY/Z in Pseudomonas aeruginosa. (2016) Front Microbiol. 2;7:247.
7.	Guo Q, Wei Y, Xia B, Jin Y, Liu C, Pan X, Shi J, Zhu F, Li J, Qian L, Liu X, Cheng Z, Jin S, Lin J, Wu W. Identification of a small molecule that simultaneously suppresses virulence and antibiotic resistance of Pseudomonas aeruginosa. (2016) Sci Rep. 6:19141.
8.	Jin Y, Jin S, Wu W. Regulation of bacterial gene expression by ribosome stalling and rescuing.(2015) Curr Genet. Nov 26
9.	Shi J, Jin Y, Bian T, Li K, Sun Z, Cheng Z, Jin S, Wu W. SuhB is a novel ribosome associated protein that regulates expression of MexXY by modulating ribosome stalling in Pseudomonas aeruginosa. (2015) Mol Microbiol. 98(2):370-83.
10.	Jia J, Bai F, Jin Y, Santostefano KE, Ha UH, Wu D, Wu W, Terada N, Jin S. Efficient Gene Editing in Pluripotent Stem Cells by Bacterial Injection of Transcription Activator-Like Effector Nuclease Proteins. (2015) Stem Cells Transl Med.;4(8):913-26. 
11.	Li Y, Bai F, Xia H, Zhuang L, Xu H, Jin Y, Zhang X, Bai Y, Qiao M. A novel regulator PA5022 (aefA) is involved in swimming motility, biofilm formation and elastase activity of Pseudomonas aeruginosa. Microbiol Res. 2015 Jul;176:14-20.
12.	Neeld D, Jin Y, Bichsel C, Jia J, Guo J, Bai F, Wu W, Ha UH, Terada N, Jin S. Pseudomonas aeruginosa injects NDK into host cells through a type III secretion system. (2014) Microbiology. 160(Pt 7):1417-26.
13.	Jia J, Jin Y, Bian T, Wu D, Yang L, Terada N, Wu W, Jin S. (2014) Bacterial delivery of TALEN proteins for human genome editing.PLoS One. 11;9(3):e91547.
14.	Sun Z, Shi J, Liu C, Jin Y, Li K, Chen R, Jin S, Wu W. PrtR homeostasis contributes to Pseudomonas aeruginosa pathogenesis and resistance against ciprofloxacin. (2014) Infect Immun. 82(4):1638-47.
15.	Li K, Xu C, Jin Y, Sun Z, Liu C, Shi J, Chen G, Chen R, Jin S, Wu W. SuhB is a regulator of multiple virulence genes and essential for pathogenesis of Pseudomonas aeruginosa.(2013) MBio. 4(6):e00419-13.
16.	Jin Y, Yang H, Qiao M, Jin S. MexT regulates the type III secretion system through MexS and PtrC in Pseudomonas aeruginosa. J Bacteriol. 2011 Jan;193(2):399-410.
17.	Jin Y, Li T, Xia H, Gu C, Zhang X, Bai Y, Xu H, Qiao M. Mutational analysis of genes involved in elastin hydrolysis in Pseudomonas aeruginosa. Wei Sheng Wu Xue Bao. 2008 Dec;48(12):1623-8. Chinese


联系方式: 办公电话 022-23507018         电子邮件 yxjin@nankai.edu.cn

::主要学术论文::
::主要科研项目::