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刘燕强

 性    别:男
 职    称:教授
 所属部门:动物生物学和发育生物学系
 招生专业:动物学
 研究方向:神经功能调控
::教师简介::
    1985年湖南农业大学学士,1989年山西农业大学硕士,1996年南京农业大学(农业部动物生理生化开放实验室)理学博士,1989-1993年湖南湘大实业公司动物营养工程师,1996-1998年军事医学科学院博士后研究,2003年和2006年曾在意大利比萨大学访问研究和合作研究;现为南开大学生命科学学院教授,博士研究生导师,兼任动物生物学与发育生物学系教工党支部书记、副系主任和实验室主任。任主要承担《动物生理学实验》和《神经生物学》本科课程;《高级动物生理学》和《动物生理学专题》等研究生课程。主编和参编10余部教材和专著,获天津市和南开大学教学成果奖多项,指导的硕士论文曾获2013年南开大学和2015年度天津市优秀论文。曾主持完成过国家自然科学基金、国家教育部骨干教师基金、留学回国人员基金和国际合作等科研项目多项,已在国内外期刊发表论文80余篇。目前在研项目包括国家自然科学基金面上项目(胞外游离锌离子在急性脑缺血致神经死亡中的意义)和天津市自然科学基金项目(大豆异黄酮调控Papez回路内记忆相关信号通路的研究)等。

联系信息
地址:天津市卫津路94号南开大学生命科学学院第4教学楼,300071
电话:022-23508378
E-mail:liuyanq@nankai.edu.cn,liuyanq2@126.com

主要学术论文

1. He CC, Wang ZY,  Tian K,  Liu W, Li YB,  Hong Y,  Yu LX, Pang W*, Jiang YG* , Liu YQ*. DNA methylation mechanism of intracellular zinc deficiency-induced injury in primary hippocampal neurons in the rat brain, Nutritional Neuroscience, 2017, DOI 10.1080/1028415X. 2017. 1312090  
2. Wang YX, Tian K, He CC, Ma X L, Zhang F, Wang HG, An Di, Heng B, Jiang YG, Liu YQ*. Genistein inhibits hypoxia, ischemic-induced death, and apoptosis inPC12 cells. Environmental Toxicology and Pharmacology,  2017,50: 227–233 
3.Tian K, He CC,Xu HN, Wang YX,  Wang HG, An Di, Heng B, Pang W, Jiang YG* , Liu YQ*.  Zn2+reduction induces neuronal death with changes in voltage-gatedpotassium and sodium channel currents. Journal of Trace Elements in Medicine and Biology,  2017,41: 66–74 
4.Zhang F, Ma XL, Wang YX, He CC, Tian K, Wang HG, An Di, Heng B, Xie LH, Liu YQ*. TPEN, a specific Zn2+ chelator, inhibits sodium dithionite and glucose deprivation (SDGD)-induced neuronal death by modulating apoptosis, glutamate signaling, and voltage-gated K+ and Na+ channels. Cell Mol Neurobiol. 2017, 37:235–250 (DOI 10.1007/s10571-016-0364-1) 
5.Ma XL, Zhang F, Wang YX, He C, Tian K, Wang HG, An Di, Heng B, Liu YQ *. Genistein inhibition of OGD-induced brain neuron death correlates with its modulation of apoptosis, voltage-gated potassium and sodium   currents and glutamate signal pathway. Chemico-Biological Interactions, 2016, 254:73-82
6.Zhang F, Ma XL, Wang YX, Su RR, He C, Tian K, Liu YQ *. Detection of four different amino acid neurotransmitters in cultured rat neurons and the culture medium by pre-column derivatization HPLC. NeuroReport, 2016, 27:495–500
7.Wang YX,Zhang F, Ma X L, He C, Tian K, Wang HG, An Di, Heng B, Xie LH, Liu YQ *.  Oxygen/Glucose Deprivation (OGD) Enhancement of Cell Death/Apoptosis in PC12 Cells and Hippocampal Neurons Correlates with Changes in Neuronal Excitatory Amino Acid Neurotransmitter Content and Potassium Currents. NeuroReport, 2016, 27:617–626
8.Hu YD, Pang W, He CC, Lu H, Liu W, Wang ZY, Liu YQ, Huang CY & Jiang YG. The cognitive impairment induced by zinc deficiency in rats aged 0~2 months related to BDNF DNA methylation changes in the hippocampus, Nutr Neurosci, 2016,DOI: 10.1080/1028415X.2016.1194554
9.Wang WM, Liu Z, Liu AJ, Wang YX, Wang HG, An D, Heng B, Xie LH, Duan JL, Liu YQ *.The Zinc Ion Chelating Agent TPEN Attenuates Neuronal Death/apoptosis Caused by Hypoxia/ischemia Via Mediating the Pathophysiological Cascade Including Excitotoxicity, Oxidative Stress, and Inflammation. CNS Neurosci Ther 21 (2015) 708–717
10.Liu Z, Huang YY, Wang YX, Wang HG, Deng F, Heng B, Xie LH, Liu YQ*. Prevention of cell death by the zinc ion chelating agent TPEN in cultured PC12 cells exposed to Oxygen–Glucose Deprivation (OGD). J Trace Elem Med Bio 31 (2015) 45–52
11.Tian RY, Li YX, Zhu LN, Li SP, Heng B, Liu YQ*. Regulation of arterial blood pressure by electrical stimulation of the mammillary body and its surrounding areas in rabbits. In 2014 International Conference on Biological Engineering and Biomedical (ISBN: 978-1-60595-162-1). Lancaster : DEStech Publications Inc.,March,2014. P.150-158
12.Wang SJ, Xie LH, Heng B, Liu Y Q*. Classification of potassium and Chlorine ionic currents in retinal ganglion cell line (RGC-5). Vision Neurosci,2012, 29, 275–282
13.Liu YQ*, Xin TR, Liang JJ, Wang WM, Zhang YY. Memory ability of chronic aluminium exposed mice in response to soy isoflavones treatment. Phytother  Res 2010, 24: 1451–1456
14.Ristori C, Cammalleri M, Liu YQ, Casini G, Dal Monte, Bagnoli P*. Involvement of the cAMP-dependent pathway in the reduction of epileptiform bursting caused by somatostatin in the mouse hippocampus. N S Arch Pharmacol.2008, 378:563-577
15.Liu YQ*, Xin TR, Lü XY. Memory ability of hypercholesterolemic mice in response to treatment with soy isoflavones. Neurosci Res. 2007,57:544-549.
16.Li XL, Wu ZL, Liu YQ, Liu ZZ, Wang XJ, Xin TR. & Ji Q. Single-nucleotide polymorphism identification in the caprine myostatin gene. J. Anim. Breed. Genet 2006,123: 141–144 
17.Wu ZL, Li XL, Liu YQ, Gong YF, Liu ZZ, Wang XJ, Xin TR, Ji Q. The red head and neck of Boer goats may be controlled by the recessive allele of the MC1R gene. Anim. Res. 2006,55:313–322
18.Liu YQ, Qiang Z, Wu ZL, Ji Q. The expression and role of soma tosta tin and its receptors in the developing retina. Chin J Ophthalmol 2006,42:111-114
19.Cammalleri M, Cervia D, Liu YQ, Dal Monte M, Kreienkamp HJ, Allen J P., Richter D and Bagnoli P*. A role of somatostatin receptor subtype I (sst1) in spontaneous epileptiform activity in mouse hippocampus. Eur J Neurosci. 2004, 20: 2711-2721
::主要学术论文::
::主要科研项目::