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赵强(男)

 性    别:男
 职    称:研究员
 所属部门:生物化学和分子生物学系
 招生专业:高分子化学与物理,生物化学
 研究方向:生物材料
::教师简介::
个人简介:
    男,工学博士,研究员,国家优秀青年科学基金获得者。
    2001年9月本科毕业于西北工业大学高分子材料与工程专业,2001-2006年在天津大学材料学院材料学专业攻读硕、博士学位,分别于2004年3月和2006年9月获得工学硕士和博士学位。2006年至2009年在香港城市大学(City University of Hong Kong)从事博士后研究(Research Fellow)。2009年11月至今在南开大学生科院生物活性材料教育部重点实验室工作,任副教授、教授(博导)。期间于2014年4-5月在英国Queen Mary University of London和King's College London访问学习。以通讯/第一作者在生物材料及医学领域国际权威学术期刊J Am Soc Nephrol、Biomaterials、J Control Release等发表SCI收录论文50余篇(累计影响因子>200),论文被包括Sci Transl Med等权威期刊引用或评述>1000次。	


联系方式:
Email:qiangzhao@nankai.edu.cn
Tel: 022-83662855


研究方向:
1. 功能化人工血管的设计与构建
2. 一氧化氮(NO)控释生物材料

学术兼职:
1. 中国生理学会基质生物学分会委员暨青年学组副组长
2. 中国生物材料学会再生医学材料分会委员
3. 中国生物医学工程学会组织工程与再生医学分会委员
4. 中国医药教育协会医疗器械管理专业委员会委员
5. 中国老年保健医学研究会现代医疗保健研究分会氧化损伤与衰老防治专家委员会委员
6. 美国化学会(ACS)会员
7. BioMed Research International客座编辑(Guest Editor)
8. Journal of Analytical & Molecular Techniques期刊编委
9. Austin Journal of Biomedical Engineering期刊编委

承担项目:
1. 国家优秀青年科学基金项目“心血管生物材料” (项目批准号:81522023),项目负责人
2. 国家自然科学基金重大研究计划(培育项目)“通过仿生天然细胞外基质构建功能型人工血管促进组织再生重构” (项目批准号:91639113),项目负责人
3. 国家自然科学基金(面上项目) “具有微/纳米复合纤维结构的小口径人工血管构建及对组织再生的引导作用” (项目批准号:81371699)  项目负责人
4. 国家自然科学基金(青年基金) “人工血管材料的多重功能化修饰及空间分布调控” (项目批准号:81000680)  项目负责人
5. 国家自然科学基金 (国际(地区)合作与交流项目)“用于血管再生的新型生物材料研究” (项目批准号:81310108034)  项目负责人
6. 高等学校博士学科点专项科研基金(新教师类)“活性人工血管的构建和功能评价”(项目批准号:20100031120021) 项目负责人
7. 天津市应用基础与前沿技术研究计划(自然科学基金)青年项目资金“通过可控降解和功能梯度改善细胞向支架材料内生长” (项目批准号:12JCQNJC09300) 项目负责人
8. 分子科学国家实验室开放基金“具有可控释放一氧化氮(NO)功能的心血管生物材料研究” 项目负责人


著作章节:
1. Zhao Q, Cheng GX. Biodegradable PHB/PEG derivatives and their degradation behavior. In: New Frontiers in Polymer Research Edited by Bregg RK. Nova Science Publishers Inc, New York, US, 2006, p99-124.

代表论文:(*通讯作者)
1. Feng G, Zhang J, Li Y, Nie Y, Zhu D, Wang R, Liu J, Gao J, Liu N, He N, Du W, Tao H, Xu Y*, Kong D, Zhao Q*, Li Z*. IGF-1C modified hydrogel enhances cell therapy for acute kidney injury. J Am Soc Nephrol 2016, 27: 2357-69 (with editorial). (IF: 8.491, JCR一区)

2. Yao X, Liu Y, Gao J, Yang L, Mao D, Stefanitsch C, Li Y, Zhang J, Ou L, Kong D, Zhao Q*, Li Z*. Nitric oxide releasing hydrogel enhances the therapeutic efficacy of mesenchymal stem cells for myocardial infarction. Biomaterials 2015, 60: 130-40. (IF: 8.387, JCR一区)

3. Wang Z, Cui Y, Wang J, Yang X, Wu Y, Wang K, Gao X, Li D, Li Y, Zheng X, Zhu Y, Kong D*, Zhao Q*. The effect of thick fibers and large pores of electrospun poly(ε-caprolactone) vascular grafts on macrophage polarization and arterial regeneration. Biomaterials 2014, 35: 5700-10. (IF: 8.387, JCR一区)

4. Zhao Q, Zhang J, Song L, Ji Q, Yao Y, Cui Y, Shen J*, Wang P, Kong D*. Polysaccharide-based biomaterials with on-demand nitric oxide releasing property regulated by enzyme catalysis. Biomaterials 2013, 34: 8450-8. (IF: 8.387, JCR一区)

5. Zheng W, Wang Z, Song L, Zhao Q*, Zhang J, Li D, Wang S, Zheng X, Han J, Yang Z, Kong D*. Endothelialization and patency of RGD-functionalized vascular grafts in a rabbit carotid artery model. Biomaterials 2012, 33: 2880-91. (IF: 8.387, JCR一区)

6. Wang Z, Lu Y, Qin K, Tian Y, Wang J, Zhang J, Cui Y, Wu Y, Hou J, Shen J, Xu Q, Kong D, Zhao Q*. Enzyme-functionalized vascular grafts catalyze in-situ release of nitric oxide from exogenous NO prodrug. J Control Release 2015, 210: 179-88. (IF: 7.441, JCR一区)

7. Wang W, Song H, Zhang J, Li P, Li C*, Wang C, Kong D, Zhao Q*. An injectable, thermosensitive and multicompartment hydrogel for simultaneous encapsulation and independent release of a drug cocktail as an effective combination therapy platform. J Control Release, 2015, 203: 57-66. (IF: 7.441, JCR一区)

8. Zhang J, Wang J, Wei Y, Gao C, Chen X, Kong W, Kong D*, Zhao Q*. ECM-mimetic heparin glycosamioglycan-functionalized surface favors constructing functional vascular smooth muscle tissue in vitro. Colloids Surf B: Biointerfaces 2016, 146: 280-8.(IF: 3.902)

9. Zhou X, Zhang J, Feng G, Shen J, Kong D*, Zhao Q*. Nitric oxide-releasing biomaterials for biomedical applications. Curr Med Chem, 2016, 23: 2579-601. (IF: 3.455)

10. Lou S, Gao S, Wang W, Zhang M, Zhang J, Wang C, Li C*, Kong D, Zhao Q*. Galactose-functionalized multi-responsive nanogels for hepatoma-targeted drug delivery. Nanoscale 2015, 7: 3137-46. (IF: 7.76, JCR二区)

11. Gao J, Zheng W, Zhang J, Guan D, Yang Z*, Kong D, Zhao Q*. Enzyme-controllable delivery of nitric oxide from a molecular hydrogel. Chem Commun 2013, 49:9173-5. (IF: 6.834, JCR二区) 

12. Yao Y, Wang J, Cui Y, Xu R, Wang Z, Zhang J, Wang K, Li Y , Zhao Q*, Kong D. Effect of sustained heparin release from PCL/Chitosan hybrid small-diameter vascular grafts on the anti-thrombogenic property and endothelialization. Acta Biomater 2014, 10:2739-49. (IF: 6.025, JCR一区) 

13. Ji Q, Zhang S, Zhang J, Wang Z, Wang J, Cui Y, Pang L, Wang S, Kong D, Zhao Q*. Dual functionalization of poly(ε-caprolactone) (PCL) film surface through supramolecular assembly with the aim of promoting in-situ endothelial progenitor cell attachment on vascular grafts. Biomacromolecules 2013, 14: 4099-107. (IF: 5.750, JCR一区) 

14. Zhao Q, Wang S, Cheng X, Yam RCM, Kong D, Li RKY. Surface modification of cellulose fiber via supramolecular assembly of biodegradable polyesters by the aid of host-guest inclusion complexation. Biomacromolecules 2010, 11: 1364-9. (IF: 5.750, JCR一区)

15. Wang K, Chen X, Pan Y, Cui Y, Zhou X, Kong D, Zhao Q*. Enhanced vascularization in hybrid PCL/gelatin fibrous scaffolds with sustained release of VEGF. BioMed Res Int 2015, Article ID 865076. (IF: 2.134)

16. Zhao Q, Li Z*. Angiogenesis. BioMed Res Int 2015, Article ID 135861. (IF: 2.134)

17. Li Q, Wang Z, Zhang S, Zheng W, Zhao Q*, Zhang J, Wang L*, Wang S, Kong D. Functionalization of the surface of electrospun poly(epsilon-caprolactone) mats using zwitterionic poly(carboxybetaine methacrylate) and cell-specific peptide for endothelial progenitor cells capture. Mater Sci Eng C-Mater Biol Appl 2013, 33: 1646-53. (IF: 3.088).
 
18. Zhang M, Wang K, Wang Z, Xing B, Zhao Q*, Kong D*. Small-diameter tissue engineered vascular graft made of electrospun PCL/Lecithin blend. J Mater Sci: Mater Med 2012, 23:2639-48. (IF: 2.587) 

19. Zhao Q, Wang S, Kong M, Geng W, Li RKY, Song C, Kong D. Phase-morphology, physical properties, and biodegradation behavior of novel PLA/PHBHHx blends. J Biomed Mater Res 2012, 100B: 23-31. (IF: 2.759)

20. Zhao Q, Yam RCM, Zhang B, Yang Y, Cheng X, Li RKY. Novel all-cellulose ecocomposites prepared in ionic liquids. Cellulose 2009, 16: 217-26. (* Twenty most frequently requested scientific contributions in 2009) (IF: 3.573, JCR一区)

21. Zhao Q, Zhang B, Quan H, Yam RCM, Yuen RKK, Li RKY. Flame retardancy of rice husk-filled high-density polyethylene ecocomposites. Compos Sci Technol 2009, 69: 2675-81. (IF: 3.569, JCR一区)

22. Zhao Q, Cheng G, Li H, Ma X, Zhang L. Synthesis and Characterization of biodegradable poly(3-hydroxybutyrate) and poly(ethylene glycol) multiblock copolymers. Polymer 2005, 46: 10561-7. (IF: 3.562, JCR二区)

23. Zhao Q, Tao J, Yam RCM, Mok ACK, Li RKY, Song C. Biodegradation behavior of polycaprolactone /rice husk ecocomposites in simulated soil medium. Polym Degrad Stab 2008, 93: 1571-6. (IF: 3.163, JCR二区)

24. Zhao Q, Cheng G, Song C, Zen Y, Tao J, Zhang L. Crystallization behavior and biodegradation of poly(3-hydroxybutyrate) and poly(ethylene glycol) multiblock copolymers. Polym Degrad Stab 2006, 91: 1240-6. (IF: 3.163, JCR二区)

25. Zhao Q, Cheng G. Preparation of biodegradable poly(3-hydroxybutyrate) and poly(ethylene glycol) multiblock copolymers. J Mater Sci 2004, 39: 3829-31. (IF: 2. 371)

授权专利:
1. 赵强,孔德领,张计敏,王淑芳. 酶催化可控释放一氧化氮的新型生物材料及其制备方法与应用, 中国发明专利, 专利号: ZL201310296773.4.

::主要学术论文::
::主要科研项目::