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王恺

 性    别:男
 职    称:副研究员
 所属部门:生物化学和分子生物学系
 招生专业:
 研究方向:组织工程;人工血管
::教师简介::
个人简介:
王恺于2007.06年在郑州大学生物工程系获得学士学位。随后,考入南开大学生物化学与分子生物专业进行硕士和博士阶段的学习,于2013年6月获得博士学位。2013年7月进入南开大学生物活性材料教育部重点实验室工作, 主要从事生物活性人工血管的构建与体内植入评价。 发表SCI论文 15篇,参编外文专著一部。
E-Mail:wkcs424@163.com

Personal profile:
Kai Wang obtained his Bsc. in Biothechnology (2007) from Zhengzhou University. Subsequently, He obtained his Ph.D in Biochemistry and Molecular Biology (2013) from Nankai University, where his Ph.D was supervised by Professor Deling Kong. After finshed the PH.D, he joined Nankai University in July 2013, where he is currently a lecture in the College of Life Sciences and Key Laboratory of Bioactive Materials, Ministry of Education. His current research interest focuses on the design and fabrication of bioactive vascular grafts as well as in vivo evaluation of them. To date, he has published around 15 papers as the corresponding/first author in the journals such as Adv Healthc Mater, Tissue Eng Part A and J Biomed Mater Res A.
E-Mail:wkcs424@163.com

Main publications:
1.Wang, K.; Zheng, W.; Pan, Y.; Ma, S.; Guan, Y.; Liu, R.; Zhu, M.; Zhou, X.; Zhang, J.; Zhao, Q., Three-Layered PCL Grafts Promoted Vascular Regeneration in a Rabbit Carotid Artery Model. Macromolecular bioscience 2016. 16, 608-618.
2.Zhao, L.; Ma, S.; Pan, Y.; Zhang, Q.; Wang, K.*; Song, D.; Wang, X.; Feng, G.; Liu, R.; Xu, H., Functional Modification of Fibrous PCL Scaffolds with Fusion Protein VEGF‐HGFI Enhanced Cellularization and Vascularization. Advanced Healthcare Materials 2016, 5 (18), 2376-2385.
3.Wang, H.; Mao, D.; Wang, Y.; Wang, K.*; Yi, X.; Kong, D.; Yang, Z.; Liu, Q.; Ding, D., Biocompatible fluorescent supramolecular nanofibrous hydrogel for long-term cell tracking and tumor imaging applications. Scientific reports 2015, 5.
4.Wang, K.; Chen, X.; Pan, Y.; Cui, Y.; Zhou, X.; Kong, D.; Zhao, Q., Enhanced vascularization in hybrid PCL/gelatin fibrous scaffolds with sustained release of VEGF. BioMed research international 2015, 2015.
5.An, J.1; Wang, K.1; Chen, S.; Kong, M.; Teng, Y.; Wang, L.; Song, C.; Kong, D.; Wang, S., Biodegradability, cellular compatibility and cell infiltration of poly (3-hydroxybutyrate-co-4-hydroxybutyrate) in comparison with poly (ε-caprolactone) and poly (lactide-co-glycolide). Journal of Bioactive and Compatible Polymers: Biomedical Applications 2015, 30 (2), 209-221.
6.Wang, K.; Zhu, M.; Li, T.; Zheng, W.; Xu, L. L.; Zhao, Q.; Kong, D.; Wang, L., Improvement of cell infiltration in electrospun polycaprolactone scaffolds for the construction of vascular grafts. Journal of biomedical nanotechnology 2014, 10 (8), 1588-1598.
7.Wang, K.; Xu, M.; Zhu, M.; Su, H.; Wang, H.; Kong, D.; Wang, L., Creation of macropores in electrospun silk fibroin scaffolds using sacrificial PEO‐microparticles to enhance cellular infiltration. Journal of Biomedical Materials Research Part A 2013, 101 (12), 3474-3481.
8.Zhang, M.1; Wang, K.1; Wang, Z.; Xing, B.; Zhao, Q.; Kong, D., Small-diameter tissue engineered vascular graft made of electrospun PCL/lecithin blend. Journal of Materials Science: Materials in Medicine 2012, 23 (11), 2639-2648.
9.Wang, K.; Guan, Y.; Liu, Y.; Zhu, M.; Li, T.; An, D.; Ou, L.; Che, Y.; Zhang, G.; Zhang, J., Fibrin glue with autogenic bone marrow mesenchymal stem cells for urethral injury repair in rabbit model. Tissue Engineering Part A 2012, 18 (23-24), 2507-2517.

发表专著:
1.Polymerric Biomaterials for Tissue Regeneration. Springer. 2016. (以第一作者完成Chapter11: Regeneration of Blood Vessel

主持科研项目:
1.国家自然科学基金青年项目“生物活性人工血管体内降解及血管再生调控”。 经费:23万;执行年限:2015.01-2017.12;项目批准号:81401534。
2.天津市自然科学基金青年项目“结构设计及功能修饰构建新型小口径人工血管”。 经费:6万;执行年限:2014.04-2017.03;项目批准号:14JCQNJC13900。
3.中国博士后科学基金面上资助“可诱导平滑肌细胞取向再生的小口径人工血管的研究” 经费:5万;执行年限:2014.09-2017.09;项目批准号:2014M561177。
4.南开大学与天津医院合作项目“纤维环支架材料的设计与制备”。经费:10万;执行年限:2016.12-2019.12;项目批准号:BE119461
5.聚合物分子工程国家重点实验室开放研究课题“PCL/PDO复合血管材料的体内植入研究”。经费:3万;执行年限:2015.01-2015.11;项目批准号:K2015-19
6.中央高校基本科研业务费“结构设计及功能修饰构建新型小口径人工血管”,经费:15万;执行年限:2014.01-2015.12;项目批准号:65141004
::主要学术论文::
::主要科研项目::