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张钧

 性    别:男
 职    称:副研究员
 所属部门:生物化学和分子生物学系
 招生专业:生物化学及分子生物学
 研究方向:生物医学工程
::教师简介::
学习和工作经历:
1997.9-2001.7   吉林大学生命科学学院  学士
2001.9-2004.7  南开大学生命科学学院  硕士
2004.7-2007.5   南开大学生命科学学院  博士
2007.5-2010.4   美国加州洛杉矶分校  博士后                          


研究方向:
1. 生物方法构建组织工程人工血管
2. 心血管疾病的机制研究


代表论文:
1.	ZX Wang, B Sun, M Zhang, LL Ou , YZ Che, Jun Zhang*, DL Kong*. Functionalization of electrospun poly(ε-caprolactone) scaffold with heparin and vascular endothelial growth factors for potential application as vascular grafts. Journal of Bioactive and Compatible Polymers. 2013, 28(2) :154–166
2.	K Wang, Y Guan, Y Liu, MF Zhu, T Li, D An, LL Ou, YZ Che, GR Zhang, Jun Zhang*, Xi-Long Zheng, and Deling Kong*. Fibrin Glue with Autogenic Bone Marrow Mesenchymal Stem Cells for Urethral Injury Repair in Rabbit Model. Tissue Engineering Part A. December 2012, 18(23-24): 2507-2517.
3.	Jun Zhang, JY Youn, AY Kim, R Ramirez, L Gao, D Ngo, PengChen, Jennifer Scovotti, A Mahajan and H Cai* NOX4-dependent hydrogen peroxide overproduction in human atrial fibrillation and HL-1 atrial cells: relationship to hypertension. Front. Physiol. 2012, Volume3 140|1
4.	W Zheng , Z Wang , L Song , Q Zhao, Jun Zhang, D Li, S Wang ,J Han, X Zheng, Z Yang, D Kong. Endothelialization and patency of RGD-functionalized vascular grafts in a rabbit carotid artery model. Biomaterials  2012, 33: 2880-2891. 
5.	CH Yang, DX Li, Z Liu, G Hong, Jun Zhang*, DL Kong, ZM Yang*. Responsive Small Molecular Hydrogels Based on Adamantane-Peptides for Cells Culture. The Journal of Physical Chemistry B. 2012 Jan 12;116(1):633-8. 
6.	ZH Wang, HM Wang, WT Zheng, Jun Zhang, Q Zhao, SF Wang, ZM Yang, DL Kong. Highly stable surface modifications of poly(3-caprolactone) (PCL) films by molecular self-assembly to promote cells adhesion and proliferation. Chem Commun (Camb). 2011 Aug 21;47(31):8901-3. 
7.	Jun Zhang, LY Wang, G Hu, MY He, YT Yu, DL Kong. Enhancement of gene delivery by DNA linked on PEI/PCL electrospun fibers. J Biomed Mater Res A. 2011;96(1):212-220.
8.	Jun Zhang, H Cai. Netrin-1 Prevents Ischemia/Reperfusion-induced Myocardial Infarction via DCC-dependent Nitric Oxide Production. J. Mol Cell Cardiol. 2010;48(6):1060-70.			
9.	Ling Gao, YF Pung, Jun Zhang, P Chen, T Wang, M Li, M Meza, L Toro, H Cai. Sepiapterin reductase regulation of endothelial tetrahydrobiopterin and nitric oxide bioavailability. Am. J. Physiol. Heart Circ. Physiol. (2009) Jul;297(1):H331-9. 
10.	Y Guan, LL Ou, G Hu, H Wang, Y Xu, JT Chen, Jun Zhang, YT Yu, DL Kong. Tissue engineering of urethra using human VEGF165 gene modified bladder urothelial cells. Artificial organs 2007;32(2):91–99.			
11.	Jun Zhang, HX Qi, LL Ou, P Hu, SH Guo, YT Yu, DL Kong. Engineering of Vascular Grafts with Genetically Modified Bone Marrow Mesenchymal Stem Cells on Poly (propylene carbonate) Graft. Artificial Organs. 2006; 30(12):898-906  
12.	Jun Zhang, Y Zhang, YJ Duan, LL Ou, YT Yu, DL Kong. Study of Bone Marrow Derived Stem Cells and Gene Therapy for Engineering of Cardiovascular Grafts. Key Engineering Materials 2005;VoLs 288-289:31-34			 
::主要学术论文::
::主要科研项目::