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周浩

 性    别:男
 职    称:副教授
 所属部门:生物化学和分子生物学系
 招生专业:生物化学与分子生物学
 研究方向:蛋白质的结构与功能研究
::教师简介::
周浩,男,现任南开大学生命科学学院副教授,硕士生导师;
1999.9-2003.6 湖北农学院 生物技术专业 获得学士学位;
2003.9-2008.6 南开大学 生物化学与分子生物学专业 获得博士学位;
2008.7-2013.12年 南开大学 生命科学学院 讲师;
2013.12-至今 南开大学 生命科学学院 副教授 硕士生导师;

研究方向:蛋白质结构与功能;基于结构的蛋白质工程及应用
E-mail:haozhou@nankai.edu.cn

近五年发表文章:
[1] Shi, Yang; Zhou, Hao; Zhang, Xiaoli; Wang, Jingyu; Long, Jiafu; *Yang, Zhimou; *Ding, Dan. Self-assembling choline mimicks with enhanced binding affinities to C-LytA protein. Scientific Reports, 4, pp 1-5, 2014.
[2] Zhang, Xiaoli; Zhou, Hao; Xie, Ying; Ren, Chunhua; *Dan, Ding; * Long, Jiafu; *Yang, Zhimou Rational Design of Multifunctional Hetero-Hexameric Proteins for Hydrogel Formation and Controlled Delivery of Bioactive Molecules. Advanced healthcare materials, 2014.
[3] Du, Xiao; Wang, Jingyu; Diao, Wentao; Wang, Ling; *Long, Jiafu; *Zhou, Hao. A Genetically Modified Protein-Based Hydrogel for 3D Culture of AD293 Cells. PLos One, 9(9), e107949, 2014.
[4] Lv, Chunmei; Gao, Xiang; Li, Wenfei; Xue, Bo; Qin, Meng; Burtnick, Leslie D.; Zhou, Hao; *Cao, Yi; *Robinson, Robert C.; *Wang, Wei. Single-molecule force spectroscopy reveals force-enhanced binding of calcium ions by gelsolin. Nature Communications, 5(4623), 2014.
[5] Diao, Wentao; Yang, Xue; *Zhou, Hao. Purification, crystallization and preliminary X-ray data collection of the N-terminal domain of the 26S proteasome regulatory subunit p27 and its complex with the ATPase domain of Rpt5 from Mus musculus. Acta crystallographica Section F, Structural biology communications, 70, pp 611-615, 2014.
[6] Jiang, Dunquan; Zhang, Qingqing; Zheng, Qianqian; Zhou, Hao; Jin, Jin; *Zhou, Weihong; *Bartlam, Mark; Rao, Zihe. Structural analysis of Mycobacterium tuberculosis ATP-binding cassette transporter subunit UgpB reveals specificity for glycerophosphocholine. FEBS Journal, 281(1), pp 331-341, 2014.
[7] Chi, Wenhao; Liu, Shuai; Yang, Jixiang; Wang, Ruiyu; Ren, Hongqi; *Zhou, Hao; Chen, Jiatong; *Guo, Tianying. Evaluation of the effects of amphiphilic oligomers in PEI based ternary complexes on the improvement of pDNA delivery. Journal of Materials Chemistry B, 2(33), pp 5387-5396, 2014.
[8] Chu, Xinlei; Qin, Xiaohong; Xu, Huisha; Li, Lei; Wang, Zheng; Li, Fengzhi; Xie, Xingqiao; Zhou, Hao; *Shen, Yuequan; *Long, Jiafu. Structural insights into Paf1 complex assembly and histone binding. Nucleic Acids Research, 41(22), pp 10619-10629, 2013.
[9] Wang, Jingyu; Zhang, Jinxiu; Zhang, Xiaoli; *Zhou, Hao. A Protein-Based Hydrogel for In Vitro Expansion of Mesenchymal Stem Cells. PLos One, 8(9), e75727, 2013.
[10] Wang, Huaimin; Han, Aitian; Cai, Yanbin; Xie, Ying; *Zhou, Hao; *Long, Jiafu; *Yang, Zhimou. Multifunctional biohybrid hydrogels for cell culture and controlled drug release. Chemical Communications, 49(67), pp 7448-7450, 2013.
[11] Liu, Ruming; Tian, Xueying; Huang, Xitai; *Zhou, Hao. Transfer of Ser7 Phosphorylated CENP-A from Centromere to Midbody During Mitosis in MCF-7 Cells. Folia Biologica, 59(3), pp 105-109, 2013.
[12] Xie Xingqiao; Yan Xiaojie; Wang Zheng; Zhou Hao; Diao Wentao; Zhou Weihong; *Long Jiafu; *Shen Yuequan. Open–closed motion of Mint2 regulates APP metabolism. Journal of Molecular Cell Biology, 0, pp 1-9, 2012.
[13] Wang, Zheng; Yang, Xue; Chu, Xinlei; Zhang, Jinxiu; Zhou, Hao; *Shen, Yuequan; *Long, Jiafu. The structural basis for the oligomerization of the N-terminal domain of SATB1. Nucleic Acids Research, 40(9), pp 4193-4202, 2012.
[14] Zhang, Jinxiu; Yang, Xue; Wang, Zheng; Zhou, Hao; Xie, Xingqiao; *Shen, Yuequan; *Long, Jiafu. Structure of an L27 Domain Heterotrimer from Cell Polarity Complex Patj/Pals1/Mals2 Reveals Mutually Independent L27 Domain Assembly Mode. Journal of Biological Chemistry, 287(14), pp 11132-11140, 2012.
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