靳永新

靳永新，女，博士，副教授。2002-2006年于南开大学生命科学学院攻读学士学位。2006-2011年于南开大学生命科学学院微生物学专业免试攻读博士学位，期间于2009-2011年赴美国佛罗里达大学进行联合培养。2011年开始在南开大学生命科学学院微生物系工作，2016年底晋升为副教授，主要研究致病菌的毒力因子及耐药性相关基因调控。目前主持天津市自然科学基金一项，国家自然科学基金一项。作为第一作者或通讯作者在Molecular Microbiology,Journal of Bacteriology, Frontiers in Microbiology, Fems Microbiology Letters等期刊上发表文章

2002 南开大学 学士 2006 南开大学 博士 2009--2011 美国佛罗里达大学 联合培养博士

2011--2016 南开大学生命科学学院 讲师 2016-- 南开大学生命科学学院 副教授

■ 致病菌毒性基因的表达调控及作用机制
■ 致病菌耐药机理研究

 

1.      Yin L, Liu Q, Pan X, Lv C, Bai Y, Bai F, Cheng Z, Wu W, Ha UH, Jin Y*. MvaT binds to the P _exsC promoter to repress the type III secretion system in Pseudomonas aeruginosa,Front Cell Infect Microbiol., 2023,13:1267748.

2.      Yang F, Zhou Y, Bai Y, Pan X, Ha UH, Cheng Z, Wu W, Jin Y*, Bai F*. MvfR controls tolerance to polymyxin B by regulating rfaD in Pseudomonasaeruginosa, Microbiol Spectr. 2023, 11(3): e0042623.

3.       Wang D, Zhang X, Yin L, Liu Q, Yu Z, Xu C, Ma Z, Xia Y, Shi J, Gong Y, Bai F, Cheng Z, Wu W, Lin J, Jin Y*. RplI interacts with 5' UTR of exsA to repress its translation and type III secretion system in Pseudomonas aeruginosa, PLoS Pathog., 2022, 18(1): e1010170.

4.       Liu Q, Yin L, Lv C, Bai F, Cheng Z, Wu W, Jin Y*. Parallel Evolution to Elucidate the Contributions of PA0625 and parE to Ciprofloxacin Sensitivity in Pseudomonas aeruginosa. Microorganisms, 2022 Dec 21;11(1):13.

5.       Liu Q, Yin L, Zhang X, Zhu G, Liu H, Bai F, Cheng Z, Wu W, Jin Y*. Reversion of Ceftazidime Resistance in Pseudomonas aeruginosa under Clinical Setting.Microorganisms, 2022 Dec 2;10(12):2395

6.       Zhang X, Yin L, Liu Q, Wang D, Xu C, Pan X, Bai F, Cheng Z, Wu W, Jin Y*. NrtR Mediated Regulation of H1-T6SS in Pseudomonas aeruginosa. Microbiol Spectr., 2022, 10(1): e0185821.

7.       Ma Z^#, Xu C^#, Zhang X, Wang D, Pan X, Liu H, Zhu G, Bai F, Cheng Z, Wu W, Jin Y*. A MexR Mutation Which Confers Aztreonam Resistance to Pseudomonas aeruginosa. Front Microbiol. 2021, 12: 659808

8.       Xu C^#, Liu H^#, Pan X, Ma Z, Wang D, Zhang X, Zhu G, Bai F, Cheng Z, Wu W, Jin Y*. Mechanisms for Development of Ciprofloxacin Resistance in a Clinical Isolate of Pseudomonas aeruginosa, Front Microbiol., 2021, 11: 598291.

9.       Xu C, Wang D, Zhang X, Liu H, Zhu G, Wang T, Cheng Z, Wu W, Bai F*, Jin Y*. Mechanisms for rapid evolution of carbapenem resistance in a clinical isolate of Pseudomonas aeruginosa.Front Microbiol., 2020, 11: 1390.

10.   Jin Y^#, Zhang M^#, Zhu F, Peng Q, Weng Y, Zhao Q, Liu C, Bai F, Cheng Z, Jin S*, Wu W*. NrtR Regulates the Type III Secretion System Through cAMP/Vfr Pathway in Pseudomonas aeruginosa, Front Microbiol., 2019, 10: 85.

11.   Jin Y^#, Liu Y^#, Li Z, Santostefano K, Shi J, Zhang X, Wu D, Cheng Z, Wu W, Terada N, Jin S*, Bai F*. Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery. PLoS ONE, 2018, 13(3): e0194895.

12.   Tan H, Zhang L, Zhao Q, Chen R, Liu C, Weng Y, Peng Q, Bai F, Cheng Z, Jin S, Wu W, Jin Y*. DeaD contributes to Pseudomonas aeruginosa virulence in a mouse acute pneumonia model. FEMS Microbiol Lett. 2016 Oct;363(20): fnw227.

13.   Weng Y, Chen F, Liu Y, Zhao Q, Chen R, Pan X, Liu C, Cheng Z, Jin S, Jin Y*, Wu W*. Pseudomonas aeruginosa Enolase Influences Bacterial Tolerance to Oxidative Stresses and Virulence. Front Microbiol. 2016 Dec 15;7: 1999.

14.   Shi J^#, Jin Y^#, Bian T, Li K, Sun Z, Cheng Z, Jin S*, Wu W*. SuhB is a novel ribosome associated protein that regulates expression of MexXY by modulating ribosome stalling in Pseudomonas aeruginosa. Mol Microbiol. 2015 Oct;98(2):370-83.

15.   Jia J^#, Jin Y^#, Bian T, Wu D, Yang L, Terada N, Wu W*, Jin S*. Bacterial delivery of TALEN proteins for human genome editing. PLoS One. 2014 Mar 11;9(3): e91547.

16.   Jin Y^#, Yang H^#, Qiao M*, Jin S*. MexT regulates the type III secretion system through MexS and PtrC in Pseudomonas aeruginosa. J Bacteriol. 2011 Jan;193(2):399-410.

 

 

1. 自2012年起，承担本科生《微生物学实验》（分别为普通班，伯芩班和药学院授课）；

2. 自2014年起，承担本科生《生物技术综合实验》；

3. 自2014年起，承担部分研究生课程《微生物学前沿进展》；

4. 自2018年起，承担本科生《生物科学综合实验》。