靳永新

靳永新，女，博士，副教授。2002-2006年于南开大学生命科学学院攻读学士学位。2006-2011年于南开大学生命科学学院微生物学专业免试攻读博士学位，期间于2009-2011年赴美国佛罗里达大学进行联合培养。2011年开始在南开大学生命科学学院微生物系工作，2016年底晋升为副教授，主要研究致病菌的毒力因子及耐药性相关基因调控。目前主持天津市自然科学基金一项，国家自然科学基金一项。作为第一作者或通讯作者在Molecular Microbiology,Journal of Bacteriology, Frontiers in Microbiology, Fems Microbiology Letters等期刊上发表文章

2002 南开大学 学士 2006 南开大学 博士 2009--2011 美国佛罗里达大学 联合培养博士

2011--2016 南开大学生命科学学院 讲师 2016-- 南开大学生命科学学院 副教授

■ 致病菌毒性基因的表达调控及作用机制
■ 致病菌耐药机理研究

1. Wang D, Zhang X, Yin L, Liu Q, Yu Z, Xu C, Ma Z, Xia Y, Shi J, Gong Y, Bai F, Cheng Z, Wu W, Lin J, Jin Y*. RplI interacts with 5' UTR of exsA to repress its translation and type III secretion system in Pseudomonas aeruginosa, PLoS Pathog., 2022, 18(1): e1010170.

2. Liu Q, Yin L, Lv C, Bai F, Cheng Z, Wu W, Jin Y*. Parallel Evolution to Elucidate the Contributions of PA0625 and parE to Ciprofloxacin Sensitivity in Pseudomonas aeruginosa. Microorganisms, 2022 Dec 21;11(1):13.

3. Liu Q, Yin L, Zhang X, Zhu G, Liu H, Bai F, Cheng Z, Wu W, Jin Y*. Reversion of Ceftazidime Resistance in Pseudomonas aeruginosa under Clinical Setting.Microorganisms, 2022 Dec 2;10(12):2395

4. Zhang X, Yin L, Liu Q, Wang D, Xu C, Pan X, Bai F, Cheng Z, Wu W, Jin Y*. NrtR Mediated Regulation of H1-T6SS in Pseudomonas aeruginosa. Microbiol Spectr., 2022, 10(1): e0185821.

5. Ma Z^#, Xu C^#, Zhang X, Wang D, Pan X, Liu H, Zhu G, Bai F, Cheng Z, Wu W, Jin Y*. A MexR Mutation Which Confers Aztreonam Resistance to Pseudomonas aeruginosa. Front Microbiol. 2021, 12: 659808

6. Xu C^#, Liu H^#, Pan X, Ma Z, Wang D, Zhang X, Zhu G, Bai F, Cheng Z, Wu W, Jin Y*. Mechanisms for Development of Ciprofloxacin Resistance in a Clinical Isolate of Pseudomonas aeruginosa, Front Microbiol., 2021, 11: 598291.

7. Xu C, Wang D, Zhang X, Liu H, Zhu G, Wang T, Cheng Z, Wu W, Bai F*, Jin Y*. Mechanisms for rapid evolution of carbapenem resistance in a clinical isolate of Pseudomonas aeruginosa.Front Microbiol., 2020, 11: 1390.

8. Jin Y^#, Zhang M^#, Zhu F, Peng Q, Weng Y, Zhao Q, Liu C, Bai F, Cheng Z, Jin S*, Wu W*. NrtR Regulates the Type III Secretion System Through cAMP/Vfr Pathway in Pseudomonas aeruginosa, Front Microbiol., 2019, 10: 85.

9. Jin Y^#, Liu Y^#, Li Z, Santostefano K, Shi J, Zhang X, Wu D, Cheng Z, Wu W, Terada N, Jin S*, Bai F*. Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery. PLoS ONE, 2018, 13(3): e0194895.

10. Tan H, Zhang L, Zhao Q, Chen R, Liu C, Weng Y, Peng Q, Bai F, Cheng Z, Jin S, Wu W, Jin Y*. DeaD contributes to Pseudomonas aeruginosa virulence in a mouse acute pneumonia model. FEMS Microbiol Lett. 2016 Oct;363(20): fnw227.

11. Weng Y, Chen F, Liu Y, Zhao Q, Chen R, Pan X, Liu C, Cheng Z, Jin S, Jin Y*, Wu W*. Pseudomonas aeruginosa Enolase Influences Bacterial Tolerance to Oxidative Stresses and Virulence. Front Microbiol. 2016 Dec 15;7: 1999.

12. Shi J^#, Jin Y^#, Bian T, Li K, Sun Z, Cheng Z, Jin S*, Wu W*. SuhB is a novel ribosome associated protein that regulates expression of MexXY by modulating ribosome stalling in Pseudomonas aeruginosa. Mol Microbiol. 2015 Oct;98(2):370-83.

13. Jia J^#, Jin Y^#, Bian T, Wu D, Yang L, Terada N, Wu W*, Jin S*. Bacterial delivery of TALEN proteins for human genome editing. PLoS One. 2014 Mar 11;9(3): e91547.

14. Jin Y^#, Yang H^#, Qiao M*, Jin S*. MexT regulates the type III secretion system through MexS and PtrC in Pseudomonas aeruginosa. J Bacteriol. 2011 Jan;193(2):399-410.

1. 自2012年起，承担本科生《微生物学实验》（分别为普通班，伯芩班和药学院授课）；

2. 自2014年起，承担本科生《生物技术综合实验》；

3. 自2014年起，承担部分研究生课程《微生物学前沿进展》；

4. 自2018年起，承担本科生《生物科学综合实验》。