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Jinyongxin

Gender: female

Department: 微生物学系

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Office Location: Room 201, College of life sciences

Career: Associate professor

Major: Microbiology

Email: yxjin@nankai.edu.cn

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Education

2002 B.S. Nankai University 2006 Ph.D. Nankai University 2009--2011 Joint Ph.D. University of Florida, USA

WorkExperience

2011--2016 Nankai University College of Life Sciences, instructor 2016-- Nankai University College of Life Sciences, associate professor

Research Fields

Research Fields
■ Regulation and function of pathogenic bacterial virulence factors
■ Mechanisms of antibiotics resistance in pathogenic bacteria

Achievement

1. PutA Is Required for Virulence and Regulated by PruR in Pseudomonas aeruginosa, Zheng R, Feng X, Wei X, Pan X, Liu C, Song R, Jin Y, Bai F, Jin S, Wu W, Cheng Z. Front Microbiol, 2018, 9: 548.

2. Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery, Jin Y, Liu Y, Li Z, Santostefano K, Shi J, Zhang X, Wu D, Cheng Z, Wu W, Terada N, Jin S, Bai F. PLoS One, 2018, 13(3):e0194895.

3. PA5470 Counteracts Antimicrobial Effect of Azithromycin by Releasing Stalled Ribosome in Pseudomonas aeruginosa, Shi J, Liu Y, Zhang Y, Jin Y, Bai F, Cheng Z, Jin S, Wu W. Antimicrob Agents Chemother, 2018, 25: 62(2).

4. In vivo Host Environment Alters Pseudomonas aeruginosa Susceptibility to Aminoglycoside Antibioticsm, Pan X, Dong Y, Fan Z, Liu C, Xia B, Shi J, Bai F, Jin Y, Cheng Z, Jin S, Wu W. Front Cell Infect Microbiol, 2017, 7:83.

5. Pseudomonas aeruginosa Oligoribonuclease Contributes to Tolerance to Ciprofloxacin by Regulating Pyocin Biosynthesis, Chen F, Chen G, Liu Y, Jin Y, Cheng Z, Liu Y, Yang L, Jin S, Wu W. Antimicrob Agents Chemother, 2017, 61(3).

6.Pseudomonas aeruginosa enolase influences bacterial tolerance to oxidative stresses and virulence, Yuding Weng, Fei Chen, Yiwei Liu, Qiang Zhao, Xiaolei Pan, Chang Liu, Ronghao Chen, Zhihui Cheng, Shouguang Jin, Yongxin Jin, Weihui Wu. Frontiers in Microbiology.

7.HigB of Pseudomonas aeruginosa Enhances Killing of Phagocytes by Up-Regulating the Type III Secretion System in Ciprofloxacin Induced Persister Cell, Li M, Long Y, Liu Y, Liu Y, Chen C, Shi J, Zhang L, Jin Y, Yang L, Bai F, Jin S, Cheng Z and Wu W. Frontiers in Cellular and Infection Microbiology, 6:125.

8.DeaD contributes to Pseudomonas aeruginosa virulence in a mouse acute pneumonia model. Tan H, Zhang L, Zhao Q, Chen R, Liu C, Weng Y, Peng Q, Bai F, Cheng Z, Jin S, Wu W, Jin Y. FEMS Microbiol Lett, 363(20).

9.Oligoribonuclease is required for the type III secretion system and pathogenesis of Pseudomonas aeruginosa. Chen G, Zhao Q, Zhu F, Chen R, Jin Y, Liu C, Pan X, Jin S, Wu W, Cheng Z. Microbiological Research, 188-189:90-6.

10.Tan H, Zhang L, Weng Y, Chen R, Zhu F, Jin Y, Cheng Z, Jin S, Wu W. PA3297 Counteracts Antimicrobial Effects of Azithromycin in Pseudomonas aeruginosa. (2016) Front Microbiol.7:317.

11.Chen R, Weng Y, Zhu F, Jin Y, Liu C, Pan X, Xia B, Cheng Z, Jin S, Wu W. Polynucleotide Phosphorylase Regulates Multiple Virulence Factors and the Stabilities of Small RNAs RsmY/Z in Pseudomonas aeruginosa. (2016) Front Microbiol. 2;7:247.

12.Guo Q, Wei Y, Xia B, Jin Y, Liu C, Pan X, Shi J, Zhu F, Li J, Qian L, Liu X, Cheng Z, Jin S, Lin J, Wu W. Identification of a small molecule that simultaneously suppresses virulence and antibiotic resistance of Pseudomonas aeruginosa. (2016) Sci Rep. 6:19141.

13.Jin Y, Jin S, Wu W. Regulation of bacterial gene expression by ribosome stalling and rescuing.(2015) Curr Genet

14.Shi J, Jin Y, Bian T, Li K, Sun Z, Cheng Z, Jin S, Wu W. SuhB is a novel ribosome associated protein that regulates expression of MexXY by modulating ribosome stalling in Pseudomonas aeruginosa. (2015) Mol Microbiol. 98(2):370-83.

15.Jia J, Bai F, Jin Y, Santostefano KE, Ha UH, Wu D, Wu W, Terada N, Jin S. Efficient Gene Editing in Pluripotent Stem Cells by Bacterial Injection of Transcription Activator-Like Effector Nuclease Proteins. (2015) Stem Cells Transl Med.;4(8):913-26.

16.Li Y, Bai F, Xia H, Zhuang L, Xu H, Jin Y, Zhang X, Bai Y, Qiao M. A novel regulator PA5022 (aefA) is involved in swimming motility, biofilm formation and elastase activity of Pseudomonas aeruginosa. Microbiol Res. 2015 Jul;176:14-20.

17.Neeld D, Jin Y, Bichsel C, Jia J, Guo J, Bai F, Wu W, Ha UH, Terada N, Jin S. Pseudomonas aeruginosa injects NDK into host cells through a type III secretion system. (2014) Microbiology. 160(Pt 7):1417-26.

18.Jia J, Jin Y, Bian T, Wu D, Yang L, Terada N, Wu W, Jin S. (2014) Bacterial delivery of TALEN proteins for human genome editing.PLoS One. 11;9(3):e91547.

19.Sun Z, Shi J, Liu C, Jin Y, Li K, Chen R, Jin S, Wu W. PrtR homeostasis contributes to Pseudomonas aeruginosa pathogenesis and resistance against ciprofloxacin. (2014) Infect Immun. 82(4):1638-47.

20.Li K, Xu C, Jin Y, Sun Z, Liu C, Shi J, Chen G, Chen R, Jin S, Wu W. SuhB is a regulator of multiple virulence genes and essential for pathogenesis of Pseudomonas aeruginosa.(2013) MBio. 4(6):e00419-13.

21.Jin Y, Yang H, Qiao M, Jin S. MexT regulates the type III secretion system through MexS and PtrC in Pseudomonas aeruginosa. J Bacteriol. 2011 Jan;193(2):399-410.

22.Jin Y, Li T, Xia H, Gu C, Zhang X, Bai Y, Xu H, Qiao M. Mutational analysis of genes involved in elastin hydrolysis in Pseudomonas aeruginosa. Wei Sheng Wu Xue Bao. 2008 Dec;48(12):1623-8. Chinese

  


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