生命科学学院

科研成果

本人以第一（*）或通讯作者（^#）发表文章如下：

1. Niu Z, Guo J, Liu X, Chen M, Jin Y, Yao M, Li X, Che Q, Li S, Zhang C, Shangguan K, Wang D, Chen C, Yu W, Tan X, Ning W^#, Li L^#. Renal tubular epithelial-derived follistatin-like 1 protects against UUO-induced renal fibrosis in mice via inhibiting NF-kappaB-mediated epithelial inflammation. Theranostics.2025; 15 (6):2413-2427.

2. Liu S*, Wang R*, Li L*, Wang X, Gong J, Liu X, Song Z, Sun L, Liu X, Ning W, Song Y, Fung SY, Yang H. Designer amphiphilic helical peptide-decorated nanomicelles enable simultaneous inflammation control and triple-destruction of bacteria for treating bacterial pneumonia and sepsis. Theranostics.2025; 15 (17):9047-9072.

3. Jiao R, Li W, Gu X, Liu J, Liu Z, Hu Y, Yang Z, Liu Y, Liu X, Gu R, Li L^#, Li X^#. Lenalidomide attenuates cardiac fibrosis and inflammation induced by beta-adrenergic receptor activation. Int Immunopharmacol.2025; 158:114848.

4. You J*, Li L*, Yang H, Zhu Y, Huang X, Li M, Yuan Z, Ning W, Chen Z. Hypothyroidism is associated with radiation-induced pulmonary fibrosis. Breast.2025; 84:104591.

5. Li, L.*, Miao, J.*, Shaheen, N., Taleb, S.J, Hu, J., Ye, Q., He, J., Yan, J., Mallampalli, R.K., Zhao, J., and Zhao, Y. ISGylation of NF-kBp65 by SCFFBXL19 E3 ligase diminishes endothelial inflammation. Arterioscler Thromb Vasc Biol. 2023; 43(5): 674-683.

6. Qi, C., Cao, J., Liu, X., Chen, Q., Liang, M., Chen, Z., Feng, J., Chen, B., Ning, W.^#, and Li, L^#.Follistatin‑like 1 mitigates intermittent hypoxia‑induced melanoma lung metastasis in mice. Sleep and Breathing. 2022; 27(3):1165-1173

7. Li, L.*, Wei, J.*, Suber, T.L, Ye, Q.,Miao, J., Li, S., Taleb, S.J, Tran, K.C, Tamaskar, A.S., Zhao, J., and Zhao, Y. IL-37-induced activation of glycogen synthase kinase 3β promotes IL-1R8/Sigirr phosphorylation, internalization, and degradation in lung epithelial cells. J Cell Physiol. 2021; 236 (8):5676-5685

8. Sun, X., Zheng, W., Hua, R., Liu, Y., Wang, L., Kim, Y., Liu, X., Mimuro, H., Shen, Z^#, Li, L^#., Sei, Y^#.Macropinocytosis and SARS-CoV-2 cell entry. Blood and Genomics. 2021; 5 (1): 1-12.

9. Li, L., Wei, J., Li, S., Jacko, A.M., Weathington, N.M., Mallampalli, R.K., Zhao, J., and Zhao, Y. The deubiquitinase USP13 stabilizes the anti-inflammatory receptor IL-1R8/Sigirr to suppress lung inflammation. EbioMedicine. 2019; 45: 553-562.

10. Li, L., Wei, J., Mallampalli, R.K., Zhao, Y., and Zhao, J. TRIM21 mitigates human lung microvascular endothelial cells inflammatory responses to lipopolysaccharide. Am J Respir Cell Mol Biol. 2019; 61(6): 776-785.

11. Li, X.*, Li, L.*, Chang, Y.,Ning, W., and Liu, X. Structural and functional study of FK domain of Fstl1. 2019; Protein Science 28(10): 1819-1829.

12. Li, L.*, Ren, F.*, Qi, C., Xu, L., Fang, Y., Liang, M., Feng, J., Chen, B., Ning, W., and Cao, J. Intermittent hypoxia promotes melanoma lung metastasis via oxidative stress and inflammation responses in a mouse model of obstructive sleep apnea. Respiratory Research. 2018; 19:28.

13. Dong, Y.*, Geng, Y*., Li, L.*, Li, X., Yan, X., Fang, Y., Li, X., Dong, S., Liu, X., Li, X., et al.Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice. J Exp Med. 2015; 212:235-252.

14. Li, L., Li, X., Liu, X., Dong, Y., Geng, Y., Liu, X., and Ning, W. Expression, characterization, and preliminary X-ray crystallographic analysis of recombinant murine Follistatin-like 1 expressed in Drosophila S2 cells. Biosci Trends. 2013;7: 93-100.

李莲

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