Majianfei

Jianfei Ma, Research Fellow, doctoral supervisor. In 2023, he was appointed as the PI of both State Key Laboratory of Medicinal Chemical Biology and School of Life Sciences. His research interests are the structure and function of important protein complexes related to photosynthesis. As the first author / corresponding author, he has published 6 articles in international/domestic journals so far, such as Nature, eLife, Communications Biology, Current Biotechnology, and Chinese Journal of Nature. And 2 international / domestic invention patents were authorized.

Sep. 2015- Jul. 2019, Tsinghua University, Ph.D. of Biological Science, Supervisor: Prof. SUI, Sen-Fang (academician of Chinese Academy of Sciences) Sep. 2012- Jul. 2015, Yantai Institute of Coastal Research, Chinese Academy of Sciences, Master of Biotechnology Engineering, Supervisor: Prof. QIN, Song Sep. 2008- Jul. 2012，Zhengzhou University (ZZU), Bachelor of Bioengineering

Sep. 2023 to date, Research Fellow, State Key Laboratory of Medicinal Chemical Biology, Nankai University. Jul. 2019-Sep. 2023, Postdoc., School of Life Science, Tsinghua University, Collaborate Supervisor: Prof. SUI, Sen-Fang (academician of Chinese Academy of Sciences)

1. Structure and function of phycobilisome, phycobilisome–photosystem II supercomplex.

2. Light acclimation mechanism of red algae and cyanobacteria, and structural basis of how phycobilisomes appear and change.

3.Photoelectric conversion device made by important protein complexes related to photosynthesis, and exploration of artificial photosynthesis.

4. in situ structures of other macromolecular machines from higher-plants / cells by Cryo-ET.

Paper published：

# Co-first author；* Co-Correspondence

(1)    Emma Joy Dodson #, Jianfei Ma #, Maayan Suissa Szlejf, Yossi Paltiel, Noam Adir, Shan Sun, Sen-Fang Sui *, Nir Keren * (2023). The structural basis for light acclimation in phycobilisome light harvesting systems. Communications Biology 6(1): 1210.(IF=6.548)  https://doi.org/10.1038/s42003-023-05586-4

(2)    Meijing Li #, JianfeiMa #, Xueming Li*, Sen-Fang Sui* (2021). In situ cryo-ET structure of phycobilisome–photosystem II supercomplex from red alga. eLife 10: e69635. (IF=8.713) https://doi.org/10.7554/eLife.69635

(3)    Yanan Xiao, Jianfei Ma * (Co-Correspondence), Xin You, Sen-Fang Sui *. Structures and key bilins of red algal phycobilisomes. Chinese Journal of Nature, 2021, 43(03): 176-188. (In Chinese)https://doi.org/10.3969/j.issn.0253-9608.2021.03.003

(4)    Jianfei Ma #, Xin You #, Shan Sun #, Xiaoxiao Wang, Song Qin, Sen-Fang Sui * (2020). Structural basis for energy transfer in Porphyridium purpureum phycobilisome. Nature 579(7797): 146–151. (IF= 69.504) https://doi.org/10.1038/s41586-020-2020-7

(5)    Jun Zhang #, Jianfei Ma #, Desheng Liu, Song Qin, Shan Sun *, Jindong Zhao, Sen-Fang Sui * (2017). Structure of phycobilisome from the red alga Griffithsia pacifica. Nature 551(7678): 57-63. (IF=69.504) https://doi.org/10.1038/nature24278

(6)    Jianfei Ma, Huaxin Chen, Song Qin*, Hanzhi Lin*: Natural and artificial phycobiliprotein in application as dye-sensitized solar cell. Current Biotechnology, 2015, Volume 4, No. 3, 275-281 https://doi.org/10.2174/2211550104666151016203528

(7)    Jianfei Ma, Hanzhi Lin, Baosheng Ge, Song Qin: thermo-resisting sensitizer and its application, authorization in 12^th Apr.2017, national invention patent No. ZL201410471450.9;
PCT patent No. PCT/CN2015/080861(application No. 93017 in Luxembourg).

 

Research project ever directed or participated

(1)      State Natural Science Fund projects (youth program), No. 32000848, Cryo-EM structural research of cyanobacterial phycobilisomes, 2021/01-2022/12, 0.16 million, project director

(2)      State Natural Science Fund projects (general program), No. 32271245, in situ structures of the phycobilisome - photosystem II complexes by cryo-EM, 2023/01-2026/12, 0.58 million, participated

(3)      State Natural Science Fund projects (general program), No. 3167040659, High-resolution structure of intact phycobilisome by single-particle cryo-EM, 2017/01-2022/12, 0.67 million, participated

(4)      State Natural Science Fund projects (Special project), No. 32241030, The structure and function of cyanobacteria photosynthesis-related pigment protein complexes were studied by in situ Cryo-electron tomography, 2023/01-2026/12, 3 million, participated

(5)      State Natural Science Fund projects (the joint ISF-NSFC program), No. 31861143048, Developing a structure based high-resolution description of the dynamic response of marine light harvesting systems, 2019/01-2021/12, 1.6 million, participated

(6)      Ministry of Science and Technology the national key project, Protein with life process control special machine “High resolution Cryo- electron microscopy, the development of new technology and new method and its application in structural biology(2016YFA0501100)”Subject 1(2016/07-2021/6), 11.05 million, participated

 

Conference Report or Academic Practice

(1)    2023/7/28~31, The 8th Chinese Plant Protein Research Congress, report on Session Conference, tile as “single particle Cryo-EM and in situ structure of phycobilisomes from red alga”;

(2)    2021/10/14~18, National Annual Conference on Electron Microscopy, report on Session Conference, tile as “in situ cryo-ET structure of phycobilisome–photosystem II supercomplex from red alga”;

 

(1)      2019,2021: Shui Mu Fellow; Tsinghua University, twice

(2)      2019,2021: Advanced Innovation Fellow; Beijing Advanced Innovation Center for Structural Biology, twice

(3)      2019: Postdoctoral Foundation at Center for Life Science-Tsinghua University (Excellent)

(4)      2018: National Scholarship for Doctoral Students.

(5)      2017: Outstanding Ph.D. scholarship Excellence Award, by Beijing Advanced Innovation Center for Structure Biology, in Tsinghua University.