王春国

南开大学生命科学学院，教授、博士生导师。2022年入选农业农村部科技英才计划。长期专注园艺及药用植物重要农艺性状形成机制解析及分子育种研究。致力于综合运用遗传学、细胞生物学、基因组学及合成生物学等多学科理论和方法，开展如下研究：（1）青花菜、花椰菜等园艺作物产量、品质性状形成的调控机制及分子育种；（2）园艺及药用植物天然活性成分代谢通路解析及生物合成；（3）丹参等药用植物种质资源评价、创制及开发。在Horticulture Research、EMBO J、Plant and Cell Physiology、J Agric Food Chem、Plant Science等行业知名刊物上发表论文六十余篇。获得2017年天津市科技进步二等奖1项，2019年天津市科技进步一等奖1项，2019年农业和农村部神农中华农业科技一等奖1项。先后承担包括科技部转基因专项、973计划、国家自然科学基金、教育部博士点基金、天津市自然科学重点基金、重大科技专项等在内的近二十个科研项目，获得国家授权发明专利8项。

2001/09-2006/06 理学博士，南开大学1997/09-2001/07 本科，烟台大学

2019.01-至今，南开大学，生命科学学院，教授2009.01-2018.12, 南开大学, 生命科学学院, 副教授2013.12-2014.12, Purdue University, Horticulture and Landscape Architecture, 访问学者,合作导师：朱健康2006/09-2008/12, 南开大学, 生命科学学院，讲师

（1）青花菜、花椰菜等园艺作物产量、品质性状形成的调控机制及分子育种；（2）园艺及药用植物天然活性成分代谢通路解析及生物合成；（3）丹参等药用植物种质资源评价、创制及开发

代表性论文：

1. He L, Li L, Zhu Y, Pan Y, Zhang X, Han X, Li M, Chen C, Li H*, Wang C*. BolTLP1, a Thaumatin-like Protein Gene, Confers Tolerance to Salt and Drought Stresses in Broccoli (Brassica oleracea L. var. Italica). Int J Mol Sci. 2021, 22(20):11132.

2. Zhu YX, Li H, He LX, Zhang X, Wu M, Pan Y, Zhang XW, Li MZ,  Wang CG*. Transcriptome and Proteins Analysis Reveals the Gene Regulatory Processes Mediated by LaAP2L1, an AP2/ERF Transcription Factor, Functioning in Fast-Growing Heterosis in Larix kaempferi. Journal of Plant Growth Regulation, 2022:1-12.

3. Lixia He, Yu Wang, Yinglan Jia, Yaling Yang, Xue Han, Jiye Yuan, Lihong Li, Peng Li, Chengbin Chen, Wenqin Song, Min Liu, Hui Li, Chunguo Wang*. Ectopic overexpression of bol-miR390a from broccoli (Brassica oleracea L var. italica) increases lateral branches in Arabidopsis. Plant growth regulation, 2020, 92, 547–558.

4. Sun D#, Wang C#, Zhang X#, Zhang W#, Jiang H, Yao X, Liu L, Wen Z, Niu G, Shan X. Draft genome sequence of cauliflower (Brassica oleracea L. var. botrytis) provides new insights into the C genome in Brassica species. Hortic Res. 2019，6: 82.

5. Li H, Zhang Q, Li L, Yuan J, Wang Y, Wu M, Han Z, Liu M, Chen C, Song W, Wang C*. Ectopic Overexpression of bol-miR171b Increases Chlorophyll Content and Results in Sterility in Broccoli (Brassica oleracea L var. italica). J Agric Food Chem. 2018, 66(37): 9588-9597.

6. Li H, Yuan J, Wu M, Han Z, Li L, Jiang H, Jia Y, Han X, Liu M, Sun D, Chen C, Song W, Wang C*. Transcriptome and DNA methylome reveal insights into yield heterosis in the curds of broccoli (Brassica oleracea L var. italic). BMC Plant Biol. 2018, 18(1):168.

7. Wang H, Wei T, Wang X, Zhang L, Yang M, Chen L, Song W, Wang C*, Chen C*. Transcriptome Analyses from Mutant Salvia miltiorrhiza Reveals Important Roles for SmGASA4 during Plant Development. Int J Mol Sci. 2018, 19(7). pii: E2088.

8. Li H, Wang Y, Wu M, Li L, Li C, Han Z, Yuan J, Chen C, Song W, Wang C*. Genome-Wide Identification of AP2/ERF Transcription Factors in Cauliflower and Expression Profiling of the ERF Family under Salt and Drought Stresses. Front Plant Sci. 2017, 8: 946.

9. Li H, Wang Y, Wu M, Li L, Jin C, Zhang Q, Chen C, Song W, Wang C*. Small RNA Sequencing Reveals Differential miRNA Expression in the Early Development of Broccoli (Brassica oleracea var. italica) Pollen. Front Plant Sci. 2017, 8: 404.

10. Li H, Liu Q, Zhang Q, Qin E, Jin C, Wang Y, Wu M, Shen G, Chen C, Song W, Wang C*. Curd development associated gene (CDAG1) in cauliflower (Brassica oleracea L. var. botrytis) could result in enlarged organ size and increased biomass. Plant Science. 2017, 254:82-94.

11. Ai Li, Jing Wang, Hui Li, Chengbin Chen, Wenqin Song*, Chunguo Wang*. Transcriptome profiling and characterization of gene families with zinc finger and nucleotide binding site (NBS) domains in Larix kaempferi. Journal of Plant Biochemistry and Biotechnology. 2017, 26: 149-159.

12.Duan CG, Wang X, Tang K, Zhang H, Mangrauthia SK, Lei M, Hsu CC, Hou YJ, Wang C, Li Y, Tao WA, Zhu JK. MET18 Connects the Cytosolic Iron-Sulfur Cluster Assembly Pathway to Active DNA Demethylation in Arabidopsis. PLoS Genet. 2015,11(10):e1005559.

13.Duan CG, Zhang H, Tang K, Zhu X, Qian W, Hou YJ, Wang B, Lang Z, Zhao Y, Wang X, Wang P, Zhou J, Liang G, Liu N, Wang C, Zhu JK. Specific but interdependent functions for Arabidopsis AGO4 and AGO6 in RNA-directed DNA methylation. EMBO J. 2015, 34(5):581-92.

14. Geng M, Li H, Jin C, Liu Q, Chen C, Song W, Wang C*. Genome-wide identification and characterization of miRNAs in the hypocotyl and cotyledon of cauliflower (Brassica oleracea L. var. botrytis) seedlings. Planta. 2014, 239:341-356.

15. Hui Li, Meijuan Geng, Qian Liu, Chuan Jin, Qingli Zhang, Chengbin Chen, Wenqin Song, Chunguo Wang*. Characteristics of cytosine methylation status and methyltransferase genes in the early development stage of cauliflower (Brassica oleracea L. var. botrytis). Plant Cell, Tissue and Organ Culture. 2014, 117: 187–199

16. Ai Li, Wen-Qin Song, Cheng-Bin Chen, Ya-Nan Zhou, Li-Wang Qi, Chun-Guo Wang*. DNA methylation status is associated with the formation of heterosis in Larix kaempferi intraspecic hybrids. Mol Breeding. 2013, 31:463-475.

17. Li A1, Zhou Y, Jin C, Song W, Chen C, Wang C*. LaAP2L1, a heterosis- associated AP2/EREBP transcript factor of Larix, increases organ size and final biomass by effecting cell proliferation in Arabidopsis. Plant and Cell Physiology. 2013, 54(11): 1822–1836.

18. Li A, Hu BQ, Xue ZY, Chen L, Wang WX, Song WQ, Chen CB, Wang CG*. DNA Methylation in genomes of several annual herbaceous and woody perennial plants of varying ploidy as detected by MSAP. Plant Mol Biol Rep. 2011, 29(4): 784-793.

19. Li A, Fang MD, Song WQ, Chen CB, Qi LW, Wang CG*. Gene expression profiles of two intraspecific Larix lines and their reciprocal hybrids. Mol Biol Rep. 2012, 39(4):3773-3784.

20. Chun-Guo WANG, Hui LI, Zhen-Yi XUE, Cheng-Bin CHEN, Yu GU, De-Ling SUN, WenQin SONG. Marker-based analysis of genomic structure and DNA methylation in a watermelon (Citrullus lanatus) ploidy series. Botanical Studies. 2009, 50: 389-402.

21. Chunguo Wang, Xiaoqiang Chen, Hui Li & Wenqin Song. RNA editing analysis of mitochondrial nad3/rps12 genes in cytoplasmic male sterility and male-fertile cauliflower By cDNA-SSCP, Botanical Studies, 2007, 48: 13-23.

22. Chunguo Wang，Xiaoqiang Chen，Tianying Lan，Hui Li，Wenqin Song. Cloning and Transcript Analyses of the Chimeric Gene Associated With Cytoplasmic Male Sterility in Cauliflower (Brassica oleracea var. botrytis). 2006, Euphytica, 151: 111–119.

天津市遗传学会副理事长、秘书长；天津市植物生理与分子生物学学会理事、副秘书长；天津市生命科学联合体秘书团成员；中国农业生物化学与分子生物学青年委员会委员。

承担本科生《细胞生物学》（市级精品课）、《遗传学》（校优秀教学团队）、《细胞生物学实验》、《细胞生物学实验》（伯苓班）、《生物科学综合实验》、《开放实验必修专题》等课程教学工作；

承担研究生《分子细胞生物学技术》、《专业硕士实践》、《农业生物工程前沿进展》等课程教学工作。