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张钧

性别: 男

部门: 生物材料与组织工程系

电话: 23501229

办公地址: 分子所107

职称: 副研究员

招生专业: 生物化学与分子生物学

邮箱: nankaizhangjun@nankai.edu.cn

通讯地址:

个人简介

学习和工作经历: 1997.9-2001.7 吉林大学生命科学学院 学士 2001.9-2004.7 南开大学生命科学学院 硕士 2004.7-2007.5 南开大学生命科学学院 博士 2007.5-2010.4 美国加州洛杉矶分校 博士后 研究方向: 1. 生物方法构建组织工程人工血管 2. 心血管疾病的机制研究

教育经历

工作经历

研究方向


研究方向:
1. 生物方法构建组织工程人工血管
2. 心血管疾病的机制研究

科研成果

1.Shi Q, Luo X,Huang Z, Midgley AC, Wang B, Liu R, Zhi D, Wei T, Zhou X, Qiao M, Zhang Jun*(责任作者), Kong D, Wang K.Cobalt-mediated multi-functional dressings promote bacteria-infected woundhealing. Acta Biomaterialia. 2018 Dec29. pii: S1742-7061(18) 30773-6. doi: 10.1016/j.actbio.2018.12.048. IF=6.383

2.Zhu M, Wu Y, Li W, Dong X, Chang H, Wang K, WuP, Zhang Jun, Fan G, Wang L, Liu J, Wang H, Kong D.Biodegradable andelastomeric vascular grafts enable vascular remodeling.Biomaterials.IF=8.82018 Nov;183:306-318.

3.Li Z#, Zhang Jun#(并列一作), LiY, Zhao S, Zhang P, Zhang Y, Bi J, Liu G, Yue Z. Carbon dots basedphotoelectrochemical sensors for ultrasensitive detection of glutathione andits applications in probing of myocardial infarction.Biosensors and Bioelectronics.15 January 2018, Volume 99, Pages 251-258 IF=8.17

4.Wang K, Zhang Q, Zhao L, Pan Y, Wang T, Zhi D,Ma S, Zhang P, Zhao T, Zhang S, Li W, Zhu M, Zhu Y, Zhang J*(责任作者), Qiao M, Kong D. Functional Modification of Electrospun Poly(ε-caprolactone) VascularGrafts with the Fusion Protein VEGF-HGFI Enhanced Vascular Regeneration.ACSAppl Mater&Interfaces. 2017 Apr 5;9(13):11415-11427.IF=8.097

5.Shuang Zhao#, Jun Zhang#(并列一作),Zhengping Li, Peixin Zhang, Yunxiao Li,Guohua Liu, Yong Wang,Zhao Yue.Photoelectrochemical determination of hydrogen peroxide using a goldelectrode modified with fluorescent gold nanoclusters and graphene oxide. MicrochimicaActa.March 2017, Volume 184, Issue3, pp 677686 IF=5.7

6.Zhao L, Ma S, Pan Y, Zhang Q, Wang K, Song D,Wang X, Feng G, Liu R, Xu H, Zhang Jun, Qiao M, Kong D.Functional Modification of Fibrous PCL Scaffolds with Fusion ProteinVEGF-HGFI Enhanced Cellularization and Vascularization.Adv Healthc Mater.2016 Sep;5(18):2376-85.IF=5.6

7.Wang K, Zheng W, Pan Y, Ma S, Guan Y, Liu R,Zhu M, Zhou X, Zhang Jun, Zhao Q, Zhu Y, Wang L, Kong D.Three-Layered PCL Grafts Promoted Vascular Regeneration in a RabbitCarotid Artery Model.Macromolecular Bioscience. 2016 Apr;16(4):608-18.IF=3.238

8.Yao X, Liu Y, Gao J, Yang L, Mao D,Stefanitsch C, Li Y, Zhang Jun, Ou L, Kong D, Zhao Q, Li Z. Nitric oxidereleasing hydrogel enhances the therapeutic efficacy of mesenchymal stem cellsfor myocardial infarction.Biomaterials. 2015Aug;60:130-40.IF=8.8

9.Ke T, Wu Y, Li L, Liu Y, Yao X, Zhang Jun*(责任作者), Kong D, Li C. Netrin-1 amelioratesmyocardial infarction-induced myocardial injury: mechanisms of action in ratsand diabetic mice.Hum Gene Ther. 2014 Sep;25(9):787-97 (IF=4.241)

10.Wenting Zheng,Di Guan,Yuxin Teng,Zhihong Wang,Suai Zhang,Lianyong Wang,Deling Kong,Jun Zhang*(责任作者). Functionalization of PCL fibrous membrane with RGD peptide by anaturally occurring condensation reaction. Chinese Science Bulletin.August 2014, 59, 22:2776-2784(IF=1.6)

11.Youn JY, Zhang Jun, Zhang Y, Chen H, LiuD, Ping P, Weiss JN, Cai H.Oxidativestress in atrial fibrillation: An emerging role of NADPH oxidase.J. Mol Cell Cardiol. 2013September, 62: 72–79(IF=5.29)2

12.Li Q, Wang Z, Zhang S, Zheng W, Zhao Q, Zhang Jun, Wang L, Wang S, Kong D.Functionalizationof the surface of electrospun poly(epsilon-caprolactone) mats usingzwitterionic poly(carboxybetaine methacrylate) and cell-specific peptide forendothelial progenitor cells capture.Mater Sci Eng C Mater Biol Appl.2013Apr 1;33(3):1646-53.(IF=2.29)

13.Wang K, Guan Y, Liu Y, Zhu M, Li T, An D, OuL, Che Y, Zhang G, Zhang Jun*(责任作者), ZhengXL, Kong D.Fibrin glue withautogenic bone marrow mesenchymal stem cells for urethral injury repair inrabbit model.Tissue Eng Part A. 2012 Dec;18(23-24):2507-17. (IF=3.5)

14.Zhexiang Wang, Bin Sun, Min Zhang, LailiangOu, Yongzhe Che, Jun Zhang*(责任作者)and Deling Kong. Functionalizationof electrospun poly(ε-caprolactone) scaffold with heparin and VEGF forpotential application as vascular grafts.Journal of Bioactive and Compatible Polymers.March 2013 vol. 28 no. 2154-166 (IF=2.5)

15.Zhang J, Youn JY, Kim AY, Ramirez RJ, Gao L, Ngo D,Chen P, Scovotti J, Mahajan A, Cai H.NOX4-DependentHydrogen Peroxide Overproduction in Human Atrial Fibrillation and HL-1 AtrialCells: Relationship to Hypertension.Front Physiol. 2012 Jun 5;3:140.(IF=4.134)

16.Zheng W, Wang Z, Song L, Zhao Q, Zhang Jun,Li D, Wang S, Han J, Zheng XL, Yang Z, Kong D.Endothelializationand patency of RGD-functionalized vascular grafts in a rabbit carotid arterymodel.Biomaterials.2012 Apr;33(10):2880-91. (IF=8.8)

17.CH Yang, DX Li, Z Liu, G Hong, Jun Zhang*(责任作者), DL Kong, ZM Yang*.Responsive Small Molecular Hydrogels Based onAdamantane-Peptides for Cells Culture.The Journal of Physical Chemistry B. 2012 Jan 12;116(1):633-8.(IF=3.146)

18.ZH Wang, HM Wang, WT Zheng, Jun Zhang, Q Zhao, SF Wang, ZM Yang,DL Kong. Highly stable surface modifications of poly(3-caprolactone) (PCL)films by molecular self-assembly to promote cells adhesion and proliferation.Chem Commun (Camb). 2011 Aug 21;47(31):8901-3. (IF=5.787)

19.Jun Zhang, LY Wang, G Hu, MYHe, YT Yu, DL Kong. Enhancement of gene delivery by DNA linked on PEI/PCLelectrospun fibers. J Biomed Mater Res A.2011;96(1):212-220.(IF=2.841)

20.Jun Zhang, H Cai. Netrin-1Prevents Ischemia/Reperfusion-induced Myocardial Infarction via DCC-dependentNitric Oxide Production. J. Mol Cell Cardiol.2010;48(6):1060-70. (IF=5.29)

21.Ling Gao, YF Pung, Jun Zhang, P Chen, T Wang, M Li, M Meza, L Toro, H Cai. Sepiapterinreductase regulation of endothelial tetrahydrobiopterin and nitric oxidebioavailability. Am. J. Physiol. Heart Circ. Physiol. (2009)Jul;297(1):H331-9. (IF=3.88)

22.Y Guan, LL Ou, G Hu, H Wang, Y Xu, JT Chen, JunZhang, YT Yu, DL Kong. Tissue engineering of urethra using human VEGF165gene modified bladder urothelial cells. Artificial organs 2007;32(2):91–99.(IF=1.87)

23.Jun Zhang, HX Qi, LL Ou, P Hu, SH Guo, YT Yu, DL Kong.Engineering of Vascular Grafts with Genetically Modified Bone MarrowMesenchymal Stem Cells on Poly (propylene carbonate) Graft. ArtificialOrgans. 2006; 30(12):898-906 (IF=1.87)

24.Jun Zhang, Y Zhang, YJ Duan, LL Ou, YT Yu, DL Kong. Study ofBone Marrow Derived Stem Cells and Gene Therapy for Engineering ofCardiovascular Grafts. Key Engineering Materials 2005;VoLs 288-289:31-34(IF=0.331)

25.HX Qi, DL Kong, P Hu, Jun Zhang, WJ Lin,F Song. Biomimic Tubulose Scaffolds with Multilayer Prepared by Electrospinningfor Tissue Engineering. Materials Science Forum 2006;Vols510-511:882-885

26.DL Kong, Jun Zhang, LL Ou, Shenqi Wang,Yaoting Yu. Novel technology in tissue engineering material research. Raremetal materials and engineering 2005; 34(2):1-5

27.Jun Zhang, DL Kong, Yaoting Yu. Implantation of vascularendothelial cell and gene theraphy of artificial organ. Chinese Journal ofclinical rehabilitation 2003; 24(7):3360-3361

28.张沛欣,马绍扬,乔明强,张钧*. 疏水蛋白HGFI用于载基因组织工程支架的研究. 南开大学学报. 201851(5)

29.王恺,马绍扬,张钧*. 利用装载内皮细胞生长因子的丝素纳米球制备具有生物活性的电纺支架材料. 南开大学学报. 2016; 49(6):80-85

30.郑文婷,关迪,王志红,孔德领,张钧*. 利用RGD肽通过天然缩合反应实现PCL纤维膜功能化. 中国科技论文.2015;12:954

31.张沛欣,马绍扬,许盼,孔德领,张钧*载有eNOS基因的PCL支架用于皮肤修复. 中国科技论文. 2015;12:1080

32.马绍扬,潘伊娃,赵立强,王恺,张钧乔明强孔德领.融合蛋白VEGF-HGFI修饰的人工血管体内移植研究. 中国科技论文. 2015;12:598

33.赵玉红,,崔建林,张翠竹,张钧,段亚君,. MOOC环境下基础实验教学中学生创新能力的培养. 实验技术与管理. 2016; Vols33(3):13-15

34., 赵玉红,,张翠竹,,段亚君,水雯箐,赵立青,李登文. 基础生物化学实验教学改革的探索与实践. 实验室研究与探索.2016;35(3):161-164

35.李欣,赵玉红,李小菊,李登文,周浩,张翠竹,张钧,张金红,赵立青. 基于拔尖人才培养的生化实验教学改革初探. 实验室研究与探索.2017;36(5):184-187

36.王淑芳,宋存江,丁丹,赵强,张钧,杨超. 应对多学科交叉融合对复合型人才培养提出的新挑战. 高校生物学教学研究. 2016;2:7-9


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