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Jun Zhou

Gender: male

Department: Genetics and Cell Biology

Tel: 022-23494816

Office Location: Biostation A403

Career: Professor

Major: Cell Biology

Email: junzhou@nankai.edu.cn

Address: 94 Weijin Road, Tianjin 300071, China

Resume

Education

Ph.D., Emory University, USA

WorkExperience

Postdoc, Genentech, Inc., USA; Professor, College of Life Sciences, Nankai University; Principal Investigator, State Key Laboratory of Medicinal Chemical Biology, Nankai University.

Research Fields

The cytoskeletal basis of development and disease.

Achievement

1.        Wang D, Li Q, Yu Z, Zhao J, Hu M, Geng X, Liu X, Zhao S, Song T, Liu M, Li D, Zhao H, Zhou J. FUT8-mediated core fucosylation stabilizes TMEM67 to promote ciliogenesis. J Cell Biol. 2025 Oct 6;224(10):e202412224.

2.        Zhai D, Li L, Wang D, Wang W, Zhao S, Wang X, Chen C, Zhu Z, Bu W, Yang M, Yin H, Shan Y, Zhao H, Westlake CJ, Lu Q, Zhou J. TBC1D20 coordinates vesicle transport and actin remodeling to regulate ciliogenesis. J Cell Biol. 2025 Apr 4;224(4):e202406139.

3.        Hong R, Tan Y, Tian X, Huang Z, Wang J, Ni H, Yang J, Bu W, Yang S, Li T, Yu F, Zhong W, Sun T, Wang X, Li D, Liu M, Yang Y, Zhou J. XIAP-mediated degradation of IFT88 disrupts HSC cilia to stimulate HSC activation and liver fibrosis. EMBO Rep. 2024 Mar;25(3):1055-1074.

4.        Li T, Liu M, Yu F, Yang S, Bu W, Liu K, Yang J, Ni H, Yang M, Yin H, Hong R, Li D, Zhao H, Zhou J. Pathologically relevant aldoses and environmental aldehydes cause cilium disassembly via formyl group-mediated mechanisms. J Mol Cell Biol. 2024 Jul 1;16(1):mjad079.

5.        Yu F, Yang S, Ni H, Heng D, Wu X, Yang M, Zhang X, Cao Y, Pei Y, An D, Li D, Liu D, Liu L, Pan L, Chen Q, Zhu X, Zhou J. O-GlcNAcylation Regulates centrosome behavior and cell polarity to reduce pulmonary fibrosis and maintain the epithelial phenotype. Adv Sci. 2023 Dec;10(36):e2303545.


Social Appointments

Teaching Experience

Cell Biology (for undergraduate students)

Advances in Cell Biology (for Ph.D. students)



Honor Title

10 Access