Zhouweihong

Dr. Weihong Zhou,graduated from Nankai University in 2001, then worked as a postdoctoral fellow at Tsinghua University, University of Georgia, and Columbia University. In 2007, she came back to Nankai University from Columbia University as an associate professor. From 2011 to 2012, she was funded by the China Scholarship Council to visit Oxford University in the UK as an visiting scholar. In 2013, she was promoted to a researcher. Her research field is structural biology. At present, her main research interest is to study the structure and function of important proteins and their complexes. She successively presided over and participated in several "863", "973" and the key R&D projects of the Ministry of Science and Technology(MOST), the International Cooperation Program of the National Natural Science Foundation of China(NSFC), and projects of the Tianjin Science and Technology Commission She has published more than 30 SCI papers so far, as the first or corresponding authors.

1987-1991: Department of Chemistry, Tianjin Normal University, B. S. degree; 1991-1995: Department of Chemistry, Tianjin Normal University, M. S. degree; 1997-2000: Department of Chemistry, Nankai University, Ph. D

1995-2003: College of Chemistry and Life Sciences, Tianjin Normal University, Tianjin, P. R. China; Assistant Professor, Lecturer; 2001-2002: Department of Life Sciences and Technology, Tsinghua University, Beijing, China; Post-doctoral Researcher 2004-2005: University of Georgia, USA, Project Coordinator 2005-2007: Columbia University, USA; Post-doc Research Fellow 2007-2013: College of Life Sciences, Nankai University, Tianjin, P. R. China; Associate Professor 2014: College of Life Sciences, Nankai University, Tianjin, P. R. China; Researcher

Main research fields:
1. Structural and functional studies on important proteins and their complexes related to human health
2. Structural and functional studies on P450 proteins

Selected Publications(corresponding author(s))

1. A Structural Model of a P450-Ferredoxin Complex from Orientation-Selective Double Electron−Electron Resonance Spectroscopy, J. Am. Chem. Soc. 2018, 140, 2514−2527

2. Structural views of quinone oxidoreductase from Mycobacterium tuberculosis reveal large conformational changes induced by the co-factor, FEBS Journal 282 (2015) 2697–2707

3. Structural analysis of Mycobacterium tuberculosis ATP-binding cassette transporter subunit UgpB reveals specificity for glycerophosphocholine, FEBS Journal 281 (2014) 331–341

4. The structure of a novel electron-transfer ferredoxin from Rhodopseudomonas palustris HaA2 which contains ahistidine residue in its iron–sulfur cluster-binding motif, Acta Cryst. (2014). D70, 1453–1464(IF：14.1)

5. Structure and function of CYP108D1 from Novosphingobium aromaticivorans DSM12444: an aromatic hydrocarbon-binding P450 enzyme, Acta Cryst. (2012). D68, 277–291 (IF：14.1)

6. Investigation of the Substrate Range of CYP199A4: Modification of the Partition between Hydroxylation and Desaturation Activities by Substrate and Protein Engineering, Chem. Eur. J. 2012, Dec 21;18(52):16677-88

Undergraduated students courses:

Biochemistry

Cell Signal Transduction

Innovation and Scientific Research Training

Graduated students courses

Modern protein engineering technology

Information retrieve

etc