陈凌懿

1.   Duan X, Wang Y, Zhang J, Zhao N, Hao Q, Yang X, Du X, Yang H, Liang H*, and Chen L*, ERK phosphorylates HNRNPF to promote the proliferation and suppress the differentiation of embryonic stem cells. Nucleic Acids Res, 2026. 54:gkaf1490. 

2.   Duan X, Zhang Q, Gao L, Ling B, Du X, and Chen L*, ERK phosphorylates ESRRB to regulate the self-renewal and differentiation of mouse embryonic stem cells. Stem Cell Reports, 2025. 20:102397. 

3.   Yu J, Zhao N, Wang Y, Ding N, Guo Z, He Z, Zhang Q, Zhang J, Yang X, Zhang M, Du X, Zhang K, and Chen L*, DCP1A, a MEK substrate, regulates the self-renewal and differentiation of mouse embryonic stem cells. Cell Rep, 2024. 43(12):115058.

4.   Nai S, Wang M, Yang J, Ling B, Dong Q, Yang X, Du X, Lu M, Liu L, Yu Z, and Chen L*, Novel role for Ddx39 in differentiation and telomere length regulation of embryonic stem cells. Cell Death Differ, 2024. 31(11):1534-1544.

5.   Dong Q, Yang X, Wang L, Zhang Q, Zhao N, Nai S, Du X, and Chen L*, Lactylation of Hdac1 regulated by Ldh prevents the pluripotent-to-2C state conversion. Stem Cell Res Ther, 2024.15(1):415.

6.   Yang X, He Z, Dong Q, Nai S, Duan X, Yu J, Zhao N, Du X, and Chen L*, Btbd8 deficiency reduces susceptibility to colitis by enhancing intestinal barrier function and suppressing inflammation. Front Immunol, 2024. 15:1382661.

7.   Dong Q, Zhang Q, Yang X, Nai S, Du X, and Chen L*, Glycolysis-Stimulated Esrrb Lactylation Promotes the Self-Renewal and Extraembryonic Endoderm Stem Cell Differentiation of Embryonic Stem Cells. Int J Mol Sci, 2024. 25(5):2692.

8.   Qin Y, Ni P, Zhang Q, Wang X, Du X, Yin Z, Wang L, Ye L*, and Chen L*, Hbxip is essential for murine embryogenesis and regulates embryonic stem cell differentiation through activating mTORC1. Development, 2022. 149(12):dev200527.

9.   Chen H, Li P, Du X, Zhao Y, Wang L, Tian Y, Song X, Shuai L*, Bai X*, and Chen L*, Homozygous Loss of Septin12, but not its Haploinsufficiency, Leads to Male Infertility and Fertilization Failure. Front Cell Dev Biol, 2022. 10:850052.

10.   Ha N, Ding N, Hong R, Liu R, Roca X, Luo Y, Duan X, Wang X, Ni P, Wu H, Zhang LF*, and Chen L*, The lupus autoantigen La/Ssb is an Xist-binding protein involved in Xist folding and cloud formation. Nucleic Acids Res, 2021. 49(20):11596-11613.

11.   Li P, Gao L, Cui T, Zhang W, Zhao Z, and Chen L*, Cops5 safeguards genomic stability of embryonic stem cells through regulating cellular metabolism and DNA repair. Proc Natl Acad Sci U S A, 2020. 117(5):2519-2525.

12.   Zhao T, Cai M, Liu M, Su G, An D, Moon B, Lyu G, Si Y, Chen L*, and Lu W*, lncRNA 5430416N02Rik Promotes the Proliferation of Mouse Embryonic Stem Cells by Activating Mid1 Expression through 3D Chromatin Architecture. Stem Cell Reports, 2020. 14:493-505.

13.  Chen H, Guo R, Zhang Q, Guo H, Yang M, Wu Z, Gao S, Liu L*, and Chen L*, Erk signaling is indispensable for genomic stability and self-renewal of mouse embryonic stem cells. Proc Natl Acad Sci U S A, 2015. 112(44):E5936-5943.

14.  Chen L and Widom J, Mechanism of transcriptional silencing in yeast. Cell, 2005. 120(1):37-48.