刘林

发布者:刘林作者:发布时间:2022-10-06浏览次数:432

代表性论文:

1. Fu H, Zhang W, Li N, Yang J, Ye X, Tian C, Lu X, Liu L: Elevated retrotransposon activity and genomic instability in primed pluripotent stem cells. Genome Biol 2021, 22(1):201.

2. Wang H, Gong P, Chen T, Gao S, Wu Z, Wang X, Li J, Marjani SL, Costa J, Weissman SM, Qi F, Pan X, Liu L: Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single-Cell Analysis of Transcriptome and Telomeres. Adv Sci (Weinh) 2021, 8(8):2004320.

3. Heng D, Sheng X, Tian C, Li J, Liu L, Gou M, Liu L: Mtor inhibition by INK128 extends functions of the ovary reconstituted from germline stem cells in aging and premature aging mice. Aging Cell 2021, 20(2):e13304.

4. Wang H, Liu L, Gou M, Huang G, Tian C, Yang J, Wang H, Xu Q, Xu GL, Liu L: Roles of Tet2 in meiosis, fertility and reproductive aging. Protein Cell 2021, 12(7):578-585.

5. Tian C, Liu L, Ye X, Fu H, Sheng X, Wang L, Wang H, Heng D, Liu L: Functional Oocytes Derived from Granulosa Cells. Cell Rep 2019, 29(13):4256-4267 e4259.

6. Zhang W, Chen F, Chen R, Xie D, Yang J, Zhao X, Guo R, Zhang Y, Shen Y, Goke J, Liu L, Lu X: Zscan4c activates endogenous retrovirus MERVL and cleavage embryo genes. Nucleic Acids Res 2019, 47(16):8485-8501.

7. Sheng X, Tian C, Liu L, Wang L, Ye X, Li J, Zeng M, Liu L: Characterization of oogonia stem cells in mice by Fragilis. Protein Cell 2019, 10(11):825-831.

8. Zhou Z, Wang L, Ge F, Gong P, Wang H, Wang F, Chen L, Liu L: Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosis. Nucleic Acids Res 2018, 46(7):3468-3486.

9. Guo R, Ye X, Yang J, Zhou Z, Tian C, Wang H, Wang H, Fu H, Liu C, Zeng M, Yang J, Liu L: Feeders facilitate telomere maintenance and chromosomal stability of embryonic stem cells. Nat Commun 2018, 9(1):2620.

10. Liu L: Linking Telomere Regulation to Stem Cell Pluripotency. Trends Genet 2017, 33(1):16-33.

11. Yang J, Guo R, Wang H, Ye X, Zhou Z, Dan J, Wang H, Gong P, Deng W, Yin Y, Mao S, Wang L, Ding J, Li J, Keefe DL, Dawlaty MM, Wang J, Xu G, Liu L: Tet Enzymes Regulate Telomere Maintenance and Chromosomal Stability of Mouse ESCs. Cell Rep 2016, 15(8):1809-1821.

12. Chen H, Guo R, Zhang Q, Guo H, Yang M, Wu Z, Gao S, Liu L, Chen L: Erk signaling is indispensable for genomic stability and self-renewal of mouse embryonic stem cells. Proc Natl Acad Sci U S A 2015, 112(44):E5936-5943.

13. Sung LY, Chang WF, Zhang Q, Liu CC, Liou JY, Chang CC, Ou-Yang H, Guo R, Fu H, Cheng WTK, Ding ST, Chen CM, Okuka M, Keefe DL, Chen YE, Liu L, Xu J: Telomere elongation and naive pluripotent stem cells achieved from telomerase haplo-insufficient cells by somatic  cell nuclear transfer. Cell Rep 2014, 9(5):1603-1609.

14. Dan J, Liu Y, Liu N, Chiourea M, Okuka M, Wu T, Ye X, Mou C, Wang L, Wang L, Yin Y, Yuan J, Zuo B, Wang F, Li Z, Pan X, Yin Z, Chen L, Keefe DL, Gagos S, Xiao A, Liu L: Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing. Dev Cell 2014, 29(1):7-19.

15. Yuan J, Zhang D, Wang L, Liu M, Mao J, Yin Y, Ye X, Liu N, Han J, Gao Y, Cheng T, Keefe DL, Liu L: No evidence for neo-oogenesis may link to ovarian senescence in adult monkey. Stem Cells 2013, 31(11):2538-2550.

16.Wang F, Pan X, Kalmbach K, Seth-Smith ML, Ye X, Antumes DM, Yin Y, Liu L, Keefe DL, Weissman SM: Robust measurement of telomere length in single cells. Proc Natl Acad Sci U S A 2013, 110(21):E1906-1912.

17. Liu M, Yin Y, Ye X, Zeng M, Zhao Q, Keefe DL, Liu L: Resveratrol protects against age-associated infertility in mice. Hum Reprod 2013, 28(3):707-717.

18. Jiang J, Lv W, Ye X, Wang L, Zhang M, Yang H, Okuka M, Zhou C, Zhang X, Liu L, Li J: Zscan4 promotes genomic stability during reprogramming and dramatically improves the quality of iPS cells as demonstrated by tetraploid complementation. Cell Res 2013,   23(1):92-106.

19. Wang F, Yin Y, Ye X, Liu K, Zhu H, Wang L, Chiourea M, Okuka M, Ji G, Dan J, Zuo B, Li M, Zhang Q, Liu N, Chen L, Pan X, Gagos S, Keefe DL, Liu L: Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells. Cell Res 2012, 22(4):757-768.

20. Liu Z, Hu Z, Pan X, Li M, Togun TA, Tuck D, Pelizzola M, Huang J, Ye X, Yin Y, Liu M, Li C, Chen Z, Wang F, Zhou L, Chen L, Keefe DL, Liu L: Germline competency of parthenogenetic embryonic stem cells from immature oocytes of adult mouse ovary. Hum Mol Genet 2011, 20(7):1339-1352.

21. Huang J, Wang F, Okuka M, Liu N, Ji G, Ye X, Zuo B, Li M, Liang P, Ge WW, Tsibris JC, Keefe DL, Liu L: Association of telomere length with authentic pluripotency of ES/iPS cells. Cell Res 2011, 21(5):779-792.

22. Liu L, Bailey SM, Okuka M, Munoz P, Li C, Zhou L, Wu C, Czerwiec E, Sandler L, Seyfang A, Blasco MA, Keefe DL: Telomere lengthening early in development. Nat Cell Biol 2007, 9(12):1436-1441.

23. Liu L, Franco S, Spyropoulos B, Moens PB, Blasco MA, Keefe DL: Irregular telomeres impair meiotic synapsis and recombination in mice. Proc Natl Acad Sci U S A 2004, 101(17):6496-6501.

24. Liu L, Trimarchi JR, Smith PJ, Keefe DL: Mitochondrial dysfunction leads to telomere attrition and genomic instability. Aging Cell 2002, 1(1):40-46.

25. Liu L, Oldenbourg R, Trimarchi JR, Keefe DL: A reliable, noninvasive technique for spindle imaging and enucleation of mammalian oocytes. Nat Biotechnol 2000, 18(2):223-225.