代表性论著 (* 通讯作者)
1. Wen, T., Du, M., Lu, Y., Jia, N., Lu, X., Liu, N., Chang, S., Zhang, X., Shen, Y.*, Yang, X.* (2025). Molecular basis of β-arrestin coupling to the metabotropic glutamate receptor mGlu3. Nat. Chem. Biol. 21, 1262–1269.
2. Lu, X., Li, D., Wang, Y., Zhang, G., Wen, T., Lu, Y., Jia, N., Wang, X., Chang, S., Zhang, X., Lin, J.*, Chen, Y.-H.*, Yang, X.*, Shen, Y.* (2025) Structural insights into the activation mechanism of the human zinc-activated channel. Nat. Comm. 16, 442.
3. Li, M., Li, Y., Lu, Y., Li, J., Lu, X., Ren, Y., Wen, T., Wang, Y., Chang, S., Zhang, X., Yang, X.*, Shen, Y.* (2023) Molecular basis of Mg2+ permeation through the human mitochondrial Mrs2 channel. Nat. Comm. 14: 4713.
4. Chen, X., Wang, Y., Li, Y., Lu, X., Chen, J., Li, M., Wen, T., Liu, N., Chang, S., Zhang, X., Yang, X.*, Shen, Y.* (2022) Cryo-EM structure of the human TACAN channel in a closed state. Cell Report. 38(9): 110445.
5. Wen, T., Wang, Z., Chen, X., Ren, Y., Lu, X., Xing, Y., Lu, J., Chang, S., Zhang, X., Shen, Y.*, Yang, X.* (2021) Structural Basis for Activation and Allosteric Modulation of Full-length Calcium Sensing Receptor. Sci. Adv. 7, eabg1483.
6. Ren, Y., Wen, T., Xi, Z., Li, S., Lu, J., Zhang, X., Yang, X.*, Shen, Y.* (2020) Cryo-EM structure of the calcium homeostasis modulator 1 channel. Sci. Adv., 6, eaba8161.
7. Liu, X., Wu, G., Yu, Y., Chen, X., Ji, R., Lu, J., Li, X., Zhang, X., Yang, X.*, Shen, Y.* (2019) Molecular understanding of calcium permeation through the open Orai channel. PLOS Biol., 17(4):e3000096.
8. Xing, Y., Wang, M., Wang, J., Nie, Z., Wu, G., Yang, X.*, Shen, Y.* (2019) Dimerization of MICU proteins controls Ca2+ influx through the mitochondrial Ca2+ uniporter. Cell Report. 26(5):1203-1212.
9. Wu, G., Yang, X.,Shen, Y.* (2018) Identification of a single aspartate residue critical for both fast and slow calcium-dependent inactivation of the human TRPML1 channel. J. Biol. Chem., 293(30):11736-11745
10. Li, X., Wu, G., Yang, Y., Fu, S., Liu, X., Kang, H., Yang. X.*, Su, X.*, Shen, Y.* (2017) Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers. Nat. Comm., 8(1), 1042. 10.1038/s41467-017-01135-w
11. Wang, L., Yang, X., Wang, Z., Liu, Y., Feng, J. Zhu, Y., Shen, Y.* (2014) Structural and Mechanistic Insights into MICU1 Regulation of Mitochondrial Calcium Uptake. EMBO J, 33(6), 594-604.
12. Yang, X., Jin, H., Cai, X., Li, S., Shen, Y.* (2012) Structural and Mechanistic Insights into the Activation of STIM1, Proc. Natl. Acad. Sci. USA, 109(15), 5657–5662. (Selected by Faculty of 1000 Biology)
书籍教材编写
1.分子生物学,普通高等教育“十一五”国家级规划教材,高等教育出版社,ISBN:978-7-04-028645-8,(2010),第十章,结构分子生物学,pp286-324。
2.慢病毒与泡沫病毒分子生物学,科学出版社,ISBN:978-7-03-034123-5,(2012),第八章,慢病毒整合酶的结构-牛免疫缺陷病毒整合酶的结构生物学,pp325-347。
3.蛋白质组学方法,科学出版社,ISBN:978-7-03-035584-3, (2012),副主编,31,9000字。