主持基金:
1. 科技部“诊疗装备与生物医用材料”重点研发计划,SQ2023YFC2400753,功能性人工血管的构建与产品研发,2024/01-2027/12,1200万元,在研,主持。
2. 一种组织工程多孔细胞外基质支架制备方法,横向转化,2024/01-2026/12,260万元,在研,主持。
3. 国家自然科学基金委员会,面上项目,82272156,机械性能增强型神经移植物联合M2巨噬细胞促进关节部位神经缺损修复及再生机制探究,2023/01-2026/12,78万元,在研,主持。
4. 国家自然科学基金委员会,面上项目,81972063,取向微纳纤维支架复合组织特异性细胞外基质水凝胶缓释M2型巨噬细胞外泌体促进肌腱原位再生,2020/01-2023/12,55万元,结题,主持。
5. 京津冀基础研究合作专项项目,22JCZXJC00100, 仿生活性纳米颗粒时序靶向人工血管促进血管再生与相关机制探究,2022/10-2025/09,60万元,在研,主持。
部分发表文章:
1. Li Y, Liu SY, Zhang JJ, Wang YM, Lu H, Zhang Y, Song G, Niu F, Shen Y, Midgley A, Li W *, Kong D*, Zhu M*. Elastic porous microspheres/extracellular matrix hydrogel injectable composites releasing dual bio-factors enable tissue regeneration. Nature communications, 2024,15, 1377.(IF:17.694,一区)(*通讯作者)
2. Du X, Wu L,Yan H, Jiang Z, Li S, Li W, Bai Y, Wang H, Cheng Z, Kong D*, Wang L*, Zhu M*. Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing. Nature communications, 2021, 12: 4733. (IF:17.694,一区)(*通讯作者)
3. Zhu M, Li W, Dong X, Yuan X, Midgley A, Chang H, Wang Y, Wang H, Wang K*, Ma PX, Wang H*, Kong D*. In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration. Nature communications, 2019, 10(1): 1-14.(IF:17.694,一区)(第一作者)
4. Dong X, Yang Y, Bao Z, Midgley AC, Li F, Dai S, Yang Z, Wang J, Liu L, Li W, Zheng Y, Liu S, Liu Y, Yu W, Liu J, Fan M*, Zhu M*, Shen Z, Gu X, Kong D*. Micro-nanofiber composite biomimetic conduits promote long-gap peripheral nerve regeneration in canine models, Bioactive Materials, 2023, 30, 98-115, (IF:16.874,一区)(*通讯作者)
5. Li L, Cao J, Li S, Cui T, Ni J, Zhang H, Zhu Y, Mao J, Gao X*, Midgley A C*, Zhu M*, Fan G*. M2 Macrophage-Derived sEV Regulate Pro-Inflammatory CCR2(+) Macrophage Subpopulations to Favor Post-AMI Cardiac Repair. Advanced Science,2023, 22, e2202964. (IF:17.521,一区)(*通讯作者)
6. Liu S, Yao L, Wang Y, Li Y, Jia Y, Yang Y, Na Li, Hu Y, Kong D, Dong X*, Wang K*, Zhu M*, Immunomodulatory hybrid micro-nanofiber scaffolds enhance vascular regeneration, Bioactive Materials, 2023, 21, 464-482. (IF:16.874,一区)(*通讯作者)
7. He X, Li W, Liu S, Li Y, Chen Y, Dan N, Dan W*, Zhu M*. Fabrication of high-strength, flexible, porous collagen-based scaffolds to promote tissue regeneration. Mater Today Bio. 2022 Aug 5;16:100376. doi: 10.1016/j.mtbio.2022.100376. (IF:10.761,一区)(*通讯作者)
8. Zhi D, Cheng Q, Midgley AC, Zhang Q, Wei T, Li Yi, Wang T, Ma T, Rafique M, Xia S, Cao Y, Li Y, Li J, Che Y, Zhu M*, Wang K*, Kong D* Mechanically reinforced biotubes for arterial replacement and arteriovenous grafting inspired by architectural engineering. Science Advances, 2022 8, eabl3888.(IF:14.957,一区)(*通讯作者)
9. Wang H, Zhou X, Wang J, Zhang X, Zhu M*, Wang H*, Fabrication of channeled scaffolds through polyelectrolyte complex (PEC) printed sacrificial templates for tissue formation, Bioactive Materials, 2022, 17: 261-275.(IF:16.874,一区)(*通讯作者)
10. Dong X, Liu S, Yang Y, Gao S, Li W, Cao J, Wan Y, Huang Z, Fan G, Chen Q, Wang H*, Zhu M*, Kong D*. Aligned microfiber-induced macrophage polarization to guide schwann-cell-enabled peripheral nerve regeneration. Biomaterials, 2021, 272: 120767. (IF:15.304,一区)(*通讯作者)
11. Li W, Bai Y, Cao J, Gao S, Xu P, Feng G, Wang L, Wang H, Kong D, Fan M*, Zhang J*, Zhu M*. Highly interconnected inverse opal extracellular matrix scaffolds enhance stem cell therapy in limb ischemia.,, 2021, 128: 209-221.(IF:10.633,一区)(*通讯作者)
12. Yan H, Mi X, A Midgley, Du X, Huang Z, Wei T, Liu R, Ma T, Zhi D, Zhu M*, Kong D*, Wang K*. Targeted Repair of Vascular Injury by Adipose-derived Stem Cells Modified with P-selectin Binding Peptide. Advanced Science, 2020, 7: 1903516. (IF:17.521,一区)(*通讯作者)
13. Wu P, Wang L, Li W, Zhang Y, Wu Y, Zhi D, Wang H, Wang L*, Kong D*, Zhu M*. Construction of vascular graft with circumferentially oriented microchannels for improving artery regeneration. Biomaterials, 2020, 119922. (IF:15.304,一区)(*通讯作者)
14. Li W, Midgley A, Bai Y, Zhu M*, Chang H, Zhu W, Wang L, Wang Y, Wang H, Kong D*. Subcutaneously engineered autologous extracellular matrix scaffolds with aligned microchannels for enhanced tendon regeneration. Biomaterials, 2019, 224:119488.(IF:15.304,一区)(*通讯作者)
15. Zhu M1, Wu Y1, Li W, Dong X, Chang H, Wang K, Wu P, Zhang J, Fan G, Wang L, Liu J, Wang H*, Kong D*. Biodegradable and elastomeric vascular grafts enable vascular remodeling. Biomaterials, 2018, 183: 306-318.(IF:15.304,一区)(并列第一作者)
16. Dong X, Yuan X, Wang L, Liu J, Midgley AC, Wang Z, Wang K, Liu J, Zhu M*, Kong D*. Construction of a bilayered vascular graft with smooth internal surface for improved hemocompatibility and endothelial cell monolayer formation. Biomaterials, 2018, 181: 1-14. (IF:15.304,一区)(*通讯作者)
17. Zhu M1, Wang Z1, Zhang J, Wang L, Yang X, Chen J, Fan G, Ji S, Xing C, Wang K, Zhao Q, Zhu Y, Kong D*, Wang L*. Circumferentially aligned fibers guided functional neoartery regeneration in vivo, Biomaterials, 2015, 61: 85-94.(IF:15.304,一区)(并列第一作者)
18. Li L, Wang Y, Guo R, Li S, Ni J, Gao S, Gao X, Mao J, Zhu Y, Wu P, Wang H, Kong D, Zhang H*, Zhu M*, Fan G*. Ginsenoside Rg3-loaded, reactive oxygen species-responsive polymeric nanoparticles for alleviating myocardial ischemia-reperfusion injury. Journal of Controlled Release. 2020, 317: 259-272. (IF:11.467,一区)(*通讯作者)
部分授权发明专利:
1. Meifeng Zhu, Deling Kong, Xianhao Dong, Guangzhou Song,Bending-resistant nerve catheter and preparation method and application thereof,美国发明专利号:US11,986,380B2。
2. Meifeng Zhu,Yueyue Yang,Wen Li, Deling Kong,Composite tubular material prepared from extracellular matrix and synthetic polymer, and preparation method thereof, 美国发明专利号:US12,090,254B2。
3. Meifeng Zhu, Wen Li, Deling Kong,Zhen Zhang, Preparation method and application of decellularized extracellular matrix tissue paper, 美国发明专利号:US 12,257,364 B2。
4. Meifeng Zhu, Guangzhou Song, Wenqian Cong, Wen Li, Kai Wang, Deling Kong,Acellular matrix woven material, preparation method and application thereof, 美国发明专利号: US 12,383,654B1。
5. 朱美峰,孔德领,王恺,王淑芳,李雯。 一种组织工程多孔细胞外基质支架制备方法。授权公告号,ZL 201510664734.4。
6. 朱美峰,孔德领,王恺,董显豪。一种三层人工血管制备技术。授权公告号:ZL 201610589001.3。
7. 朱美峰; 杨玥玥; 李雯; 孔德领。一种细胞外基质与合成聚合物复合管状材料及其制备方法。授权公告号:ZL202210845262.2。
8. 朱美峰,李雯,孔德领,张祯。 一种脱细胞基质组织纸的制备方法及应用, 授权公告号:ZL202210607526.0。
9. 朱美峰,刘思洋,董显豪,宋广州。 一种聚合物/细胞外基质微纳纤维复合材料的制备方法及其产品。授权公告号:ZL202210609275.X。
10. 朱美峰,王连永,杜欣辰,孔德领。一种多孔道烷基化壳聚糖海绵、制备方法及应用。授权专利号:ZL 202110736932.2。
11. 朱美峰,孔德领,董显豪,宋广州。一种抗弯折神经导管及其制备方法和应用。授权专利号:ZL 202210510177.0。
12. 朱美峰,李奕,孔德领,李雯,刘思洋,王宇萌。可注射细胞外基质复合多孔微球体系及制备方法。授权专利号:ZL 202211273452.8。
13. 朱美峰,王宇萌,李雯,周广东,王恺,孔德领。一种细胞负载的微纳复合纤维结构材料、制备方法及其在制备组织修复医疗器械中的应用,授权专利号:ZL202410727557.9。
14. 朱美峰,宋广州,从文倩,李雯,王恺,孔德领。名称:一种管状细胞外基质纤维支架及其制备方法与应用,专利号:2024105763629 。
15. 朱美峰,宋广州,从文倩,李雯,王恺,孔德领。一种脱细胞基质编织材料及制备方法与应用,专利号:2024105763205。
16. 李雯,朱美峰,赵彦振,杨志禄,王恺,孔德领。一种脱细胞基质管状材料及其制备方法,专利申请号:CN202411796382.3,
17. 王连永, 朱美峰, 孔德领, 王志红, 王恺, 王淑芳。一种双层结构人工血管的制备方法。授权公告号,ZL201510167670.7。
18. 但卫华,何晓棠,朱美峰,但年华。一种胶原聚集体支架材料及其制备方法。授权公告号:ZL 202210430561.X。



