代表性论文：
Hongru Zhang, Pengfei Yu, Vivek S. Tomar, Matthew J. Atherton, Zhen Lu, Angelica Ortiz, Jun Gui, N. Adrian Leu, Fangxue Yan, Andres Blanco, Mirella L. Meyer-Ficca, Ralph G. Meyer, Daniel P. Beiting, Jinyang Li, Selene Nunez-Cruz, Roddy S. O'Connor, Lexus R. Johnson, Andy J. Minn, Subin S. George, Constantinos Koumenis, J. Alan Diehl, Michael C. Milone, Hui Zheng, and Serge Y. Fuchs. Targeting ADP ribosylation to avert immunosuppression and improve CAR T therapy in solid tumors. Nature Cancer. 2022
Hongru Zhang, Vivek S. Tomar, Jinyang Li, Tara Lee Costich, Fangxue Yan, Jun Gui, Noreen McBrearty, Daniel P. Beiting, Andres Blanco, Jose R. Conejo-Garcia, Gurpanna Saggu, Allison Berger, Yulia Nefedova, Dmitry I. Gabrilovich, and Serge Y. Fuchs. Protection of the regulatory T cells from fragility in the tumor microenvironment. Cancer Immunology Research. 2022
Zheng W, Li S, Shi Z, Su K, Ding Y, Zhang L, Tang Q, Han J, Zhao H, Wang F, Zhang H*, Hong Z*. Recombinant ferritin-based nanoparticles as neoantigen carriers significantly inhibit tumor growth and metastasis. Journal of nanobiotechnology. 2024
Raghavendra Basavaraja, Hongru Zhang, A´ gnes Holczbauer, Zhen Lu, Enrico Radaelli, Charles-Antoine Assenmacher, Subin S. George, Vamshidhar C. Nallamala, Daniel P. Beiting, Mirella L. Meyer-Ficca, Ralph G. Meyer, Wei Guo, Yi Fan, Andrew J. Modzelewski, Vladimir S. Spiegelman, Michael S. Cohen, and Serge Y. Fuchs. PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies. Cell Reports Medicine. 2024
Zhen Lu , Noreen McBrearty, Jinyun Chen, Vivek S Tomar, Hongru Zhang, Gianluca De Rosa, Aiwen Tan, Aalim M Weljie, Daniel P Beiting, Zhen Miao, Subin S George, Allison Berger, Gurpanna Saggu, J Alan Diehl, Constantinos Koumenis, Serge Y Fuchs. ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes. Cell Metabolism. 2022
Eric S. Lightcap, Pengfei Yu, Stephen Grossman, Keli Song, Mithun Khattar, Kristina Xega, Xingyue He, James M. Gavin, Hisashi Imaichi, James J Garnsey, Erik Koenig, Hongru Zhang, Zhen Lu, Pooja Shah, Yu Fu, Michael A. Milhollen, Beryl A. Hatton, Jessica Riceberg, Vaishali Shinde, Cong Li, James Minissale, Xiaofeng Yang, Dylan England, Richard A. Klinghoffer, Steve Langston, Katherine Galvin, Gary Shapiro, Sai M. Pulukuri, Serge Y. Fuchs and Dennis Huszar. A small molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models. Science Translational Medicine. 2021
Jun Gui, Farima Zahedi, Angelica Ortiz, Christina Cho, Kanstantsin V. Katlinski, Kevin Alicea-Torres, Jinyang Li, Leslie Todd, Hongru Zhang, Daniel P. Beiting, Cindy Sander, John M. Kirkwood, Bryan E. Snow, Andrew C. Wakeham, Tak W. Mak, J. Alan Diehl, Constantinos Koumenis, Sandra W. Ryeom, Ben Z. Stanger, Ellen Puré, Dmitry I. Gabrilovich & Serge Y. Fuchs. Activation of p38α stress- activated protein kinase drives the formation of the pre-metastatic niche in the lungs. Nature Cancer. 2020
